蛍光抗体直接法によるアデノウイルス結膜炎の迅速診断法の検討

概要

論文の詳細を見る
We evaluated the direct immunofluorescence test for the rapid diagnosis of adenoviral conjunctivitis. Twenty-eight samples from patients suffering from acute follicular conjunctivitis of suspected adenoviral etiology were examined by the direct immunofluorescence test, enzyme-linked immunosorbent-assay (ELISA), the polymerase chain reaction (PCR) and virus isolation. Of the 28 samples, 14 (50.0%) were positive in the immunofluorescence test, 9 (32.1%) positive in ELISA, 21 (75.0%) positive in the PCR and 20 (71.4%) positive in virus isolation. The sensitivity and specificity of the immunofluorescence test were 70.0% and 100% respectively. The sensitivity of the immunofluorescence test was rather high compared with that of ELISA, which was 45.0%. The immunofluorescence test was positive in 100% of 7 samples tested within 3 days of onset of symptoms. Therefore the immunofluorescence test seems to be useful in the rapid diagnosis of early stage in adenoviral conjunctivitis.
東京女子医科大学の論文
1997-12-25