先天性筋ジストロフィーにおける感染症罹患時の一過性筋力低下(<特集>小児科学教室大澤真木子教授開講5周年記念)

概要

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The clinical manifestations were examined in 23 pediatric patients with congenital muscular dystrophy in whom transient exacerbation of muscle weakness and elevation of CK levels were associated with febrile infection, which was most common in summer. Exacerbation of muscle weakness was observed at an average of 5.4 days after infection. Exercise function levels did not decrease when the body temperature reached a maximum in any of the patients, and it took an average of 17.1 days for patients to reacquire the exercise function level. Antibody titers to Coxsackievirus were increased in 3 of 9 patients in whom virus antibody titers were determined. In 11 patients followed up for changes in serum levels of CK, serum levels were found to increase 2-fold to 7-fold when muscle weakness was noted.
東京女子医科大学の論文
2000-06-25