INFLUENCES OF COMMUNICATING FUNCTION FOR QOL IN PATIENTS WITH PARKINSON'S DISEASE UNDER STN-DBS

概要

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Deep brain stimulation (DBS) of the subthalamic nucleus (STN) has emerged as a promising treatment for medically intractable Parkinson's disease (PD). This bilateral STN-DBS ameliorated maekedly PD symptoms and motor complication, the fluctuation of medical effect, dyskinesia and dystonia. Compared with the effect of this surgical intervention for mortor function, the effect may be not enough to improve health quality of life (QOL) in patients with advanced PD. The non-motor factors, cognitive function, executive function and mood, showed a tendency to improve after STN-DBS, although there were no significant differences. In this study, we emphasized that the impairment of communicating function might be an important factor which persists despite the marked improvement of motor function observed in patients with STN-DBS surgery.
名古屋市立大学の論文
2008-07-01