212 人工心臓内の材料表面粗さによるせん断応力と血球破壊に関する研究(ライフサポートにおける工学技術)

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We have studied the relationship between shear stress generated by surface roughness and hemoiysis to develop blood compatible artificial hearts. In order to measure the shear stress due to surface roughness, we used some different viscous glycerol solutions in a rotational shear stressor, with roughed inner cylinders. The surface roughness were added to a inner cylinder surface with 0.4-0.8[μ mRa]respectively. The viscosity of glycerol solution were 3.0-12.0[mPa・s]. The stressor was rotated at 3750[s^<-1>]for 1 min and measures the torque as a function of shear stress. As a result, the torque was increased 2.4%between 0.6 and 0.8[μmRa]with 12.0[mPa・s]glycerol solution. These results were similar to results for hemolysis test with bovine blood. Therefore we consider that shear stress was generated due to surface roughness, subsequently cause hemolysis.
社団法人日本機械学会の論文
2007-09-28