249 溶血成績評価のための力学特性模擬血液

概要

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We are developing microcapsule suspensions, as model blood for absolute hemolysis evaluation. The microcapsule suspensions showed similar fractural properties to that of bovine red blood cells, under shear flow by rotational shear stressor developed in AIST. Hemolytic properties of four commercial centrifugal blood pumps, BP-80,Sarns, HPM-15 and CAPIOX, were tested using microcapsule suspensions in the mock circulation under 500 mmHg, and results were represented in NIH. The NIH tendencies of BP-80 and Sarns showed similar results between microcapsule suspensions and bovine blood. NIHs of HPM-15 and CAPIOX could not detected due to too low hemolysis levels, and the corresponding NIHs by bovine blood were smaller than those of BP-80 and Sarns. Though it is necessary to improve the capsule membrane stiffness, the microcapsule suspensions can be expected as model blood for a new hemolysis test solution.
社団法人日本機械学会の論文
2002-09-20