0941 多孔質弾性論による骨梁内間質液流れの理論的検討(S05-3 生体のシミュレーション・モデリング・計測(3),S05 生体のシミュレーション・モデリング・計測)

概要

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Interstitial fluid flow in the lacuna-canalicular system induced by bone matrix deformation is considered to play an important role in adaptive bone remodeling. Evidences from recent researches have lead to the hypothesis that osteocytes sense interstitial fluid shear stresses acting on the membranes of their osteocytic processes. In this report, we present an analytical solution of interstitial fluid pressure in a trabecula which has been modeled as a two-dimensional poroelastic material under cyclic axial loading. The solution contains steady-state response and transient response, which depend on nondimensional loading frequency Ω. Our results suggest that: (1) in the steady state, high loading frequency causes a steep fluid pressure gradient near trabecular surfaces; (2) the transient response appears when phase-shift between applied load and fluid pressure is remarkable enough to accelerate the rate of change in fluid pressure.
社団法人日本機械学会の論文
2007-09-07