不妊と肥満に関する栄養学的研究

概要

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The leptin known as ob gene regulates body weight by affecting the appetite and thermogenesis. Leptin was an important mediator of the reproductive function. In this study, they were aimed at studying causation of the infertile and the obesity on the role of nutrition. The subjects were 11 overweight women (25≦BMI) with normally ovulating, and 98 overweight women (25≦BMI) with infertile. The methods of investigation were as follows; physical measurement, biomedical testing, investigation dietary records, motion and time study and dietary habits of each subject. The concentration of serum leptin was correlated with body fat mass in the infertility and normal ovulation groups. Furthermore, the infertility groups had many intakes of the meat in comparison with the normal ovulation group. In addition, the groups had to skip a meal with dietary habits, and meal intake time was irregular. These data demonstrate that infertility groups may have reflected a nutritional abnormality, suggesting that, regarding irregularity of eating behavior and skipping meals is responsible for infertility.
昭和女子大学の論文