New Flavonoid Glycosides and Cyanogenic Glycosides from Dracocephalum peregrinum
スポンサーリンク
概要
- 論文の詳細を見る
Separation of ethyl acetate fractionation of Dracocephalum peregrinum afforded three new flavonoid glucosides (1-3), and a new cyanogenic glucoside (4). Their structures were elucidated based on HR-electron spray ionization (ESI)-MS, EI-MS, UV, IR, 1D-, and 2D-NMR data. 1-4 were tested in vitro for their antiinflammatory activity against the RAW 264.7, 293 cells. Among the compounds tested, 1-4 shown good antiinflammatory activity at 100μg/ml by the measurement of nitric oxide (NO) in lipopolysaccharide (LPS) activated macrophages. But only 2 and 3 shown weak antiinflammatory activity at 100μg/ml during the nuclear factor (NF)-κB activation assay.
- 社団法人日本薬学会の論文
- 2009-02-01
著者
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ZHANG Wei-Dong
Department of Phytochemistry, School of Pharmacy, Second Military Medical University
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SHEN Yun-Heng
Department of Phytochemistry, School of Pharmacy, Second Military Medical University
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Zhao Chun-chao
Department Of Phytochemistry School Of Pharmacy Second Military Medical University
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Zhang Wei-dong
Department Of Phytochemistry School Of Pharmacy Second Military Medical University:school Of Pharmac
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Tang Jian
School Of Pharmacy Shanghai Jiao Tong University
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Shen Yun-heng
Department Of Phytochemistry School Of Pharmacy Second Military Medical University
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Xu Xi-ke
Department Of Phytochemistry School Of Pharmacy Second Military Medical University
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FU Peng
Department of Phytochemistry, School of Pharmacy, Second Military Medical University
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Fu Peng
Department Of Phytochemistry School Of Pharmacy Second Military Medical University
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Zhang Wei-dong
School Of Pharmacy Shanghai Jiao Tong Univ.
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Zhang Wei-dong
Department Of Pharmacy School Of Stomatology Fourth Military Medical University
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Zhang Wei-Dong
Department of Natural Product Chemistry, School of Pharmacy, Second Military Medical University
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