Two New Bis-coumarin Glycosides from Daphne giraldii NITSCHE
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概要
- 論文の詳細を見る
Two new bis-coumarin glycosides were isolated from the stem barks of Daphne giraldii NITSCHE. Their structures were elucidated as 6-O-α-L-rhamnnopyranosyl daphnogirin (1), and 6-O-β-D-apiofuranosyl daphnogirin (2), on the basis of detailed spectroscopic analysis. Compounds 1 and 2 were tested inhibitory effects against production of nitric oxide (NO) in RAW264.7 cells, and cytotoxicity of human tumor cell lines A549, LOVO, QGY-7703, 6T-CEM. The results showed that compounds 1 and 2 neither reduced production of NO, nor inhibited human tumor cell lines.
- 2008-04-01
著者
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SU Juan
Department of Phytochemistry, School of Pharmacy, Second Military Medical University
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WU Zhi-Jun
Department of Research & Development, Shanghai Center of Research & Development of New Drugs
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ZHANG Wei-Dong
Department of Phytochemistry, School of Pharmacy, Second Military Medical University
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ZHANG Chuan
Department of Phytochemistry, School of Pharmacy, Second Military Medical University
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LI Hui-Liang
Department of Phytochemistry, School of Pharmacy, Second Military Medical University
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LIU Run-Hui
Department of Phytochemistry, School of Pharmacy, Second Military Medical University
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SHEN Yun-Heng
Department of Phytochemistry, School of Pharmacy, Second Military Medical University
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Zhang Wei-dong
Department Of Phytochemistry School Of Pharmacy Second Military Medical University:school Of Pharmac
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Su Juan
Department Of Phytochemistry School Of Pharmacy Second Military Medical University
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Li Hui-liang
Department Of Phytochemistry School Of Pharmacy Second Military Medical University
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Wu Zhi-jun
Department Of Research & Development Shanghai Center Of Research & Development Of New Drugs
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Zhang Chuan
Department Of Phytochemistry School Of Pharmacy Second Military Medical University
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Zhang Chuan
Department Of Neurosurgery Pet Ct Center Tianjin Medical University General Hospital
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Liu Run-hui
Dep. Of Phytochemistry School Of Pharmacy Second Military Medical Univ.
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Liu Run-hui
Department Of Phytochemistry School Of Pharmacy Second Military Medical University
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Shen Yun-heng
Department Of Phytochemistry School Of Pharmacy Second Military Medical University
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Su Juan
Department Of Dermatology Xiangya Hospital Central South University
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Zhang Wei-dong
Department Of Pharmacy School Of Stomatology Fourth Military Medical University
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Zhang Wei-Dong
Department of Natural Product Chemistry, School of Pharmacy, Second Military Medical University
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