Flavonoids from Daphne aurantiaca and Their Inhibitory Activities against Nitric Oxide Production
スポンサーリンク
概要
- 論文の詳細を見る
Chemical examination of the methanolic extract from the stem bark of Daphne aurantiaca led to the isolation of three new flavonoids (1—3), and 29 known flavonoids. All 32 compounds were isolated for the first time from Daphne aurantiaca. The isolates were tested for inhibitory activities against lipopolysaccharide (LPS)-induced nitric oxide (NO) production in RAW 264.7 macrophages. Compounds 21 and 24 showed potent inhibitory activities against the production of NO with IC50 values of 0.006 and 0.076 μM, respectively.
著者
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Zhang Wei-Dong
School of Pharmacy, Shanghai Jiao Tong University
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Tang Jian
School Of Pharmacy Shanghai Jiao Tong University
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LIU Xiao-Hua
Department of Phytochemistry, Second Military Medical University
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Zhang Wei-dong
School Of Pharmacy Shanghai Jiao Tong Univ.
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Liu Xiao-hua
Department Of Phytochemistry Second Military Medical University
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LIANG Shuang
School of Pharmacy, Shanghai Jiao Tong University
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TIAN Jun-Mian
Department of Natural Product Chemistry, School of Pharmacy, Second Military Medical University
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Feng Yi
Shanghai University of Traditional Chinese Medicine Engineering Research Center of Modern Preparatio
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Xiong Zhi
Shanghai University of Traditional Chinese Medicine Engineering Research Center of Modern Preparatio
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Xiong Zhi
Shanghai University of Traditional Chinese Medicine Engineering Research Center of Modern Preparation Technology of TCM, Ministry of Education, People's Republic of China
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Liu Xiao-Hua
Department of Natural Product Chemistry, School of Pharmacy, Second Military Medical University, People's Republic of China
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Zhang Wei-Dong
School of Pharmacy, Shanghai Jiaotong University
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Tian Jun-Mian
Department of Natural Product Chemistry, School of Pharmacy, Second Military Medical University, People's Republic of China
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Liang Shuang
School of Pharmacy, Shanghai Jiaotong University
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Feng Yi
Shanghai University of Traditional Chinese Medicine Engineering Research Center of Modern Preparation Technology of TCM, Ministry of Education, People's Republic of China
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