55(P-12) アフリカ産食用葉,フヨウに含まれる化粧品・美白作用物質の探索(ポスター発表の部)

概要

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Sierra Leone is a country located in the Middle West of Africa, where people enjoy longevity. It is interesting, therefore, to know what may be the cause of their long lives. Assuming that their foods may be related to the longevity, we started to investigate the constituents in the leaves of Hibiscus sabdariffa, which is used for diet in the country. Hibiscus sabdariffa grows in the torrid zone of Africa by origin. Previously, we isolated six compounds from the leaves of African Celosia argentea L. and investigated their effect on the skin depigmentation. In this report, we describe the isolation and identification of functional molecules in the leaves of African Hibiscus sabdariffa, and their effect on the skin depigmentation. Five compounds were isolated from the leaves of Hibiscus sabdariffa and their structures were determined based on MS, ^1H-NMR and ^<13>C-NMR spectroscopic data as kaempferol 3-O-rutinoside (1), kaempferol 3-O-glucopyranoside (2), quercetin 3-O-rutinoside (3), citrusin C (4), and corchoionoside C (5). Among them, compounds 1a (kaempfrol) and 4 (citrusin C) showed a good skin depigmentation effect.
天然有機化合物討論会の論文
2001-09-01