Age-dependent changes in the activity of serum alkailne phosphatase in laboratory beagle dogs
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概要
- 論文の詳細を見る
In order to prepare background data for toxicity studies, serum alkaline phosphatase activity in a total of 5,242 male and female beagle dogs was surveyed for the sequence of changes in activity through aging. About 95% of the beagle dogs surveyed were 5 to 12 months of age, corresponding with the age usually employed in toxicity studies. Serum alkaline phosphatase (ALP) activity, about 460 IU/l at 5 months of age, steadily decreased and reached a level about one third of that (about 160 IU/l) at 12 months of age, and remained unchanged thereafter. The above findings were essentially the same irrespective of sex and breeding colony. The present results are useful information in the evaluation of blood chemistry data in toxicity studies.
- 日本トキシコロジー学会の論文
- 2008-05-01
著者
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WATANABE Dai
Kannami Laboratory, Bozo Research Center Inc.
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HOSHIYA Toru
Kannami Laboratory, Bozo Research Center Inc.
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OKANIWA Azusa
Kannami Laboratory, Bozo Research Center Inc.
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ISHII Toshiya
Kannami Laboratory, Bozo Research Center Inc.
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OYAMADA Toshifumi
Department of Veterinary Pathology, School of Veterinary Medicine, Kitasato University
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Hoshiya Toru
Kannami Laboratory Bozo Research Center Inc.
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Watanabe Dai
Kannami Laboratory Bozo Research Center Inc.
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Watanabe D
Systems Development Labora-tory Hitachi Ltd.
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Okaniwa Azusa
Kannami Laboratory Bozo Research Center Inc.
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Ishii Toshiya
Kannami Laboratory Bozo Research Center Inc.
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MIZUGUCHI Hiroyasu
Kannami Laboratory, Bozo Research Center Inc.
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Ishikawa Tsutomu
Kannami Laboratory, Bozo Research Center Inc.
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Mizuguchi Hiroyasu
Kannami Lab. Bozo Res. Center Inc. Jpn
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Mizuguchi Hiroyasu
Kannami Laboratory Bozo Research Center Inc.
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Hori Hisako
Kannami Laboratory, Bozo Research Center Inc.
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Ishigami Makoto
Kannami Laboratory, Bozo Research Center Inc.
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Hori Hisako
Kannami Laboratory Bozo Research Center Inc.
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Ishigami Makoto
Kannami Laboratory Bozo Research Center Inc.
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Oyamada Toshifumi
Department Of Veterinary Pathology School Of Veterinary Medicine And Animal Science Kitasato Univers
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Oyamada Toshifumi
Department Of Veterinary Pathology Faculty Of Veterinary Medicine And Animal Sciences Kitasato Unive
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Ishii Toshiya
Kannami Lab. Bozo Res. Center Inc.
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Ishikawa Tsutomu
Kannami Lab. Bozo Res. Center Inc.
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Ishikawa Tsutomu
Kannami Laboratory Bozo Research Center Inc.
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Oyamada Toshifumi
Department of Veterinary Pahtology, School of Veterinary Medicine and Animal Sciences, Kitasato University
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