OE-235 Knockout of LR11 Gene, a Regulator of Migration of Intimal SMCs, Drastically Inhibits Intimal Thickning of Injured Artery in Mice(Atherosclerosis, basic-2, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
スポンサーリンク
概要
- 論文の詳細を見る
- 社団法人日本循環器学会の論文
- 2007-03-01
著者
-
SAITO Yasushi
Department of Clinical Cell Biology Graduate School of Medicine, Chiba University
-
BUJO Hideaki
Department of Genome Research and Clinical Application, Chiba University Graduate School of Medicine
-
Jiang Meizi
Department of Genome Research & Clinical Application, Chiba University Graduate School of Medicine
-
Ohwaki Kenji
Department of Genome Research & Clinical Application, Chiba University Graduate School of Medicine
-
Bujo Hideaki
筑波大学 人間総合科学研究科内分泌代謝･糖尿病内科
-
Bujo Hideaki
Department Of Genome Research & Clinical Application Chiba University Graduate School Of Medicin
-
Saito Yasushi
千葉大学 臨床遺伝子応用医学
-
Yamazaki Koji
Division of Cardiology, Department of Internal Medicine, Jikei University School of Medicine
-
Yamazaki Hiroyuki
Tokyo New Drug Research Laboratories I, Kowa Company, Ltd.
-
Unoki Hiroyuki
Division of Applied Translational Research, Graduate School of Medicine, Chiba University
-
Kanaki Tatsuro
Department of Clinical Cell Biology, Chiba University Graduate School of Medicine
-
Unoki Hiroyuki
Division Of Applied Translational Research Graduate School Of Medicine Chiba University
-
Yamazaki Hiroyuki
Tokyo New Drug Research Laboratories I Kowa Company Ltd
-
Saito Yasushi
Department Of Cardiology Juntendo University School Of Medicine
-
Yamazaki Hiroyuki
Tokyo New Drug Research Laboratories I, Kowa Company, Ltd
-
Unoki Hiroyuki
Division of Applied Translational Research, Chiba University Graduate School of Medicine
-
Yamazaki Koji
Division of Applied Translational Research, Chiba University Graduate School of Medicine
-
Ohwaki Kenji
Department of Clinical Cell Biology, Chiba University Graduate School of Medicine
関連論文
- PE-403 sLR11, an Enhancer of Intimal Smooth Muscle Cell Migration, Inhibits Fat Accumulation in Mice as a Novel Adipogenesis Regulator(PE068,Obesity/SAS 2 (H),Poster Session (English),The 73rd Annual Scientific Meeting of the Japanese Circulation Society)
- OJ-057 sLR11, a Novel Circulating Marker of Carotid Atherosclerosis, Causes an Intracellular Filament Rearrangement in Vascular Smooth Muscle Cells(OJ10,Atherosclerosis, Basic (IHD),Oral Presentation (Japanese),The 73rd Annual Scientific Meeting of The Ja
- Incremental Effects of Eicosapentaenoic Acid on Cardiovascular Events in Statin-Treated Patients With Coronary Artery Disease : Secondary Prevention Analysis From JELIS
- FRS-059 Long-term Probucol Treatment Prevents Secondary Cardiovascular Events : A Cohort Study of Patients with Heterozygous Familial Hypercholesterolemia in Japan(FRS12,New Approaches to Atherosclerosis Research (IHD),Featured Research Session (English),
- Long-Term Probucol Treatment Prevents Secondary Cardiovascular Events : a Cohort Study of Patients with Heterozygous Familial Hypercholesterolemia in Japan
- Polymorphisms of Apolipoprotein E and Methylenetetrahydrofolate Reductase in the Japanese Population
- Genetic Association of Low-Density Lipoprotein Receptor-Related Protein 2 (LRP2) with Plasma Lipid Levels
- Association of nucleotide variations in the apolipoprotein B48 receptor gene (APOB48R) with hypercholesterolemia
- Hypercholesterolemia associated with splice-junction variation of inter-α-trypsin inhibitor heavy chain 4 (ITIH4) gene
- A promoter SNP (-1323T>C) in G-substrate gene (GSBS) correlates with hypercholesterolemia
- Hypertriglyceridemia associated with amino acid variation Asn985Tyr of the RP1 gene
- PJ-507 Association of QTc Prolongation with Low Blood pH in Diabetic Patients with Acute Heart Failure Status(PJ085,Heart Failure (Pathophysiology) (M),Poster Session (Japanese),The 73rd Annual Scientific Meeting of The Japanese Circulation Society)
- Proposed Guidelines for Hypertriglyceridemia in Japan with Non-HDL Cholesterol as the Second Target
- Preventing Angiographic Progression of Coronary Atherosclerosis with Pravastatin
- Polymorphisms in Four Genes Related to Triglyceride and HDL-cholesterol Levels in the General Japanese Population in 2000
- Serum Lipid Survey and Its Recent Trend in the General Japanese Population in 2000
- PE-436 Catalytically Inactive Lipoprotein Lipase Overexpression Increases Insulin Sensitivity in Mice(Diabetes/Obesity/Metabolic syndrome-4 (H) PE73,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Societ
- PE-044 Novel Regulation Pathway of the LDL Receptor Family for Migration of Vascular Smooth Muscle Cells(Atherosclerosis, basic-3 (H) PE8,Poster Session (English),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- OJ-198 LR11, an LDL Receptor Family Member, Inhibits Adipocyte Maturation through the Induced Stabilization of Beta-catenin(Diabetes/Obesity/Metabolic syndrome-2 (H) OJ33,Oral Presentation (Japanese),The 70th Anniversary Annual Scientific Meeting of the J
- Resistin Causes Impaired Glucose Tolerance Accompanied with Decreased Insulin Sensitivities in Tissues of Mice Implanted with Resistin-overexpressing Cells (Diabetes/Obesity 6 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Enhanced Migration of Intimal Smooth Muscle Cells is Accompanied with Increased Expression of PDGF β-receptor in Explants from Rabbit Plaques (Atherosclerosis, Basic 7 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Subcutaneous Fat Alters Insulin Sensitivity by Regulation TNF-α Expression in Visceral Fat(Diabetes/Obesity 2 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Advanced Glycation End Products in Obesity and Insulin Resistance(Diabetes/Obesity 9 (H), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- LR11, an LDL Receptor Gene Family Member, is a Novel Regulator of Smooth Muscle Cell Migration(Atherosclerosis, Basic 10 (IHD), The 69th Annual Scientific Meeting of the Japanese Circulation Society)
- Clinical Features of Familial Hypercholesterolemia in Japan in a Database from 1996-1998 by the Research Committee of the Ministry of Health, Labour and Welfare of Japan
- Mutations in Japanese Subjects with Primary Hyperlipidemia : Results from the Research Committee of the Ministry of Health and Welfare of Japan since 1996
- PE-315 Vascular Effects of TAK-559, a New Potent Dual Activator of PPAR α and γ, In Hypercholesterolemic Rabbits(Atherosclerosis, Basic 4 (IHD) : PE54)(Poster Session (English))
- OJ-194 Effect of Pitavastatin on Recruitment of Bone Marrow-Derived Smooth Muscle Cells in Atheroma of ApoE-deficient Mice(Atherosclerosis, Basic 2 (IHD) : OJ22)(Oral Presentation (Japanese))
- FRS-125 Increased levels of circulating vascular endothelial growth factor is associated with visceral fat accumulation(Metabolic Syndrome (H) : FRS15)(Featured Research Session (English))
- PJ-478 Deficiency of Toll like receptor 2 ameliorates high fat-induced insulin resistance through the regulation of TNF α expression in visceral fat(Diabetes/Obesity/Metabolic syndrome(12)(H),Poster Session(Japanese),The 72nd Annual Scientific Meeting of
- PJ-683 Cytokine Production is Dependent on the Cell Size of Adipocytes in Mice(Diabetes/Obesity/Metabolic syndrome-12 (H) PJ115,Poster Session (Japanese),The 70th Anniversary Annual Scientific Meeting of the Japanese Circulation Society)
- Analysis of the Global RNA Expression Profiles of Skeletal Muscle Cells Treated with Statins
- OE-235 Knockout of LR11 Gene, a Regulator of Migration of Intimal SMCs, Drastically Inhibits Intimal Thickning of Injured Artery in Mice(Atherosclerosis, basic-2, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- Colestimide Reduces Blood Polychlorinated Biphenyl (PCB) Levels
- OJ-102 LR11, a nobel circulating marker of atherosclerosis is essential for anglotensin II -induced SMC migration(Atherosclerosis, basic(02)(IHD),Oral Presentation(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- Effects of Pioglitazone Hydrochloride on Japanese Patients with Type 2 Diabetes Mellitus
- PJ-775 Identification of TLR2 and TNFα Co-expressing Cells as Insulin Resistance-promoting Adipocytes(Diabetes/Obesity/Metabolic syndrome-12, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- PE-415 Induction of Diacylglycerol O-acyltransferase 1 Gene Induces Tumor Necrosis Factor-α Gene Expression in 3T3-L1 Adipocytes(Diabetes/Obesity/Metabolic syndrome-06, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- OE-234 A Secreted Soluble Form of LR11, Specifically Expressed in Intimal Smooth Muscle Cells, Accelerates a Formation of Lipid-Accumulated Macrophages(Atherosclerosis, basic-2, The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- FRS-025 Induced Expression of Metalloproteinase-3 Gene in Visceral Fat Tissues in the Mice Implanted with Cultured Preadipocytes(Diabetes/Obesity (basic), The 71st Annual Scientific Meeting of the Japanese Circulation Society)
- VLDL Receptor in Health and Disease : Interview with a Receptor in Avian Oocytes and Mammalian Muscle and Fat Cells
- Topical Treatment with 22-oxacalcitriol (OCT), a New Vitamin D Analogue, Caused Severe Hypercalcemia with Exacerbation of Chronic Renal Failure in a Psoriatic Patient with Diabetic Nephropathy ; A Case Report and Analysis of the Potential for Hypercalcemi
- PJ-925 A novel quantification of post-stress diastolic stunning is advantageous in identifying severe coronary artery disease(Nuclear cardiology(11)(I),Poster Session(Japanese),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- PE-435 Impact of Renal Function on B-type Natriuretic Peptide and Cardiac Function in Essential Hypertensive Patients(Hypertension, clinical(05)(H),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese Circulation Society)
- Influence of 3-hydroxy-3-methylglutaryl Coenzyme A Reductase Inhibitors on Ubiquinone Levels in Rat Skeletal Muscle and Heart : Relationship to Cytotoxicity and Inhibitory Activity for Cholesterol Synthesis in Human Skeletal Muscle Cells
- A Novel Member of the LDL Receptor Gene Family with Eleven Binding Repeats is Structurally Related to Neural Adhesion Molecules and a Yeast Vacuolar Protein Sorting Receptor
- Incidence of Symptomatic Vertebral Fracture with High-dose Glucocorticoid Treatment in the Chiba-Shimoshizu Rheumatic Cohort between 1986 and 2006
- Analysis of Genes Dominantly Expressed in Rat Cerebral Endothelial Cells Using Suppression Subtractive Hybridization
- Bone Marrow-derived Vascular Cells in Response to Injury
- PE-500 Circulation levels of soluble form of LR11, a novel migration regulator of intimal SMC, are increased in subjects with coronary stenosis(Atherosclerosis, clinical(08)(IHD),Poster Session(English),The 72nd Annual Scientific Meeting of the Japanese C
- Thirteen single-nucleotide polymorphisms in the human osteopontin gene identified by sequencing of the entire gene in Japanese individuals
- Linkage disequilibrium and haplotype analysis among ten single-nucleotide polymorphisms of interleukin 11 identified by sequencing of the gene
- Clinical Evaluation of Serum Prostate-Specific Antigen-Alpha^1-Antichymotrypsin Complex Values in Diagnosis of Prostate Cancer: A Cooperative Study
- Specific and Rapid Quantification of Viable Listeria monocytogenes Using Fluorescence in situ Hybridization in Combination with Filter Cultivation
- A nucleotide variant in the promoter region of the interleukin-6 gene associated with decreased bone mineral density
- Linkage of interleukin 6 locus to human osteopenia by sibling pair analysis
- Effects of donepezil (Aricept) on the rapid eye movement sleep of normal subjects
- Changes in Aspects Such as the Collagenous Fiber Density and Foam Cell Size of Atherosclerotic Lesions Composed of Foam Cells, Smooth Muscle Cells and Fibrous Components in Rabbits Caused by All-cis-5, 8, 11, 14, 17-icosapentaenoic Acid
- Janus kinase 3 (Jak3) is essential for common cytokine receptor γchain (γc)-dependent signaling: comparative analysis of γc, Jak3, and γc and Jak3 double-deficient mice
- Novel single nucleotide polymorphisms of the human nuclear factor kappa-B 2 gene identified by sequencing the entire gene
- Novel single nucleotide polymorphisms of the human colony-stimulating factor 2 (CSF2) gene identified by sequencing the entire gene
- Five novel single-nucleotide polymorphisms of human interferon gamma identified by sequencing the entire gene
- Pilot Study to Reduce Dioxins in the Human Body
- Enhanced expression of the LDL receptor family member LR11 increases migration of smooth muscle cells in vitro
- Isolation and radiation hybrid mapping of a highly polymorphic CA repeat sequence at the human nuclear factor kappa-beta subunit 1 (NFKB1) locus
- Epstein-Barr Virus-Associated Primary Central Nervous System Lymphoma in the Japanese Population
- MRI Detection of Suprasellar Germinoma Causing Central Diabetes Insipidus
- Significance of a Polymorphism(G->A transition) in the-75 Position of the Apolipoprotein A-1 Gene Promoter on Serum High Density Lipoprotein-Cholesterol Levels in Japanese Hyperlipidemic Subjects
- Pitavastatin Increases ABCA1 Expression by Dual Mechanisms: SREBP2-Driven Transcriptional Activation and PPARα-Dependent Protein Stabilization but Without Activating LXR in Rat Hepatoma McARH7777 Cells
- Effects of Yoku-kan-san-ka-chimpi-hange on the sleep of normal healthy adult subjects
- Hypocretin-1 (orexin-A) concentrations in cerebrospinal fluid are low in patients with Guillain-Barre syndrome
- Sleep habits of students attending elementary schools, and junior and senior high schools in Akita prefecture
- Sleep-disordered breathing in a patient with congenital myopathy
- Prevalence of sleep-related respiratory disorders in 101 schizophrenic inpatients
- Muscle sympathetic nerve activity during central, mixed and obstructive apnea : Are there any differences?
- Targeted Disruption of Smad3 Results in Enhanced Neointimal Hyperplasia through Alteration of Smooth Muscle Cell Response to TGF-β
- A highly polymorphic CA repeat marker at the human interleukin 6 receptor (IL6R) locus
- A highly polymorphic CA repeat marker at the human tumor necrosis factor alpha (TNFAα) locus
- Life Style and Cardiovascular Risk Factors in the Japanese Population-From an Epidemiological Survey on Serum Lipid Levels in Japan 1990 Part 2 : Association of Lipid Parameters with Hypertension
- Life Style and Cardiovascular Risk Factors in the Japanese Population-From an Epidemiological Survey on Serum Lipid Levels in Japan 1990 Part 1 : Influence of Life Style and Excess Body Weight on HDL-Cholesterol and Other Lipid Parameters in Men
- C-514T polymorphism in the hepatic lipase gene determines plasma lipid levels in the subjects with familial combined hyperlipidemia
- Randomized Dose-Response Study of Rosuvastatin in Japanese Patients With Hypercholesterolemia
- Different Insulin Sensitivities of Aorta and Muscle in TNF-alpha Overexpression Model by the Transplantation of Cultural Cells
- Increased circulating MDA-LDL levels in patients with coronary artery diseases and its association with the peak sizes of LDL particles
- Positive family history for CHD and "midband lipoproteins" are potential risk factors of carotid atherosclerosis in familial hypercholesterolemia
- Influence of Statins on Glucose Tolerance in Patients with Type 2 Diabetes Mellitus : Subanalysis of the Collaborative Study on Hypercholesterolemia Drug Intervention and their Benefits for Atherosclerosis Prevention (CHIBA Study)
- 4 Current Status and Problems Associated with Developing New Drugs Utilizing a Cooperative Approach Between Industry and Academia(Problems to be Resolved in the Cooperative Studies and Development of Medical Products Between Academic and Industrial Worlds
- Pitavastatin Increases ABCA1 Expression by Dual Mechanisms : SREBP2-Driven Transcriptional Activation and PPARα-Dependent Protein Stabilization but Without Activating LXR in Rat Hepatoma McARH7777 Cells
- Non-HDL Cholesterol as a Measure of Atherosclerotic Risk
- Rapid Quantitative Detection of Salmonella enterica Using Fluorescence In Situ Hybridization with Filter-cultivation (FISHFC) Method
- A 13C NMR relaxation study of octyltrimethylammonium salts in D2O.
- A 13C NMR study of octyltrimethylammonium bromide solutions with and without urea.
- Rapid Quantitative Detection of Salmonella enterica Using Fluorescence In Situ Hybridization with Filter-cultivation (FISHFC) Method