Inhibition of DNA Synthesis by SN-07, a Novel Macromolecular Antibiotic(Biological Chemistry)

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概要

• 論文の詳細を見る

• The mode of action of a novel macromolecular antibiotic, SN-07, was studied using Salmonella typhimurium TA1535, highly susceptible strain to the antibiotic. Thirty min of treatment with SN-07 at a concentration of 25μg/ml caused irreversible growth inhibition of TA1535 cells. This concentration of the antibiotic severely inhibited DNA synthesis but no effect on either RNA or protein synthesis was observed. Further, SN-07 broke down chromosomal DNA into the acid-soluble fraction.

• 社団法人日本農芸化学会の論文
• 1986-05-23

著者

• MIYATA Nobuo

  Research Institute of Life Science

• Niwano Mitsuru

  Research Institute Of Life Science Snow Brand Milk Products Co. Ltd.

• Miyata N

  Snow Brand Milk Products Co. Ltd. Tochigi Jpn

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