Studies on the Constituents of Umbelliferae Plants. XVII. Structures of Three New Ligustilide Derivatives from Ligusticum wallichii(Organic,Chemical)
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概要
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The Chinese Umbelliferae plant Ligusticum wallichii was found to contain all the new components previously found in Cnidium officinale, which is closely related with L. wallichii and is used as the source plant of the crude drug "senkyu" in Japan. Three ligustilide derivatives, senkyunolide K(2), senkyunolide L(3), and senkyunolide M(4) were isolated simultaneously and their structures were elucidated as 4β-hydroxylsenkyunolide A(2), 6-hydroxy-7-chloro-6,7-dihydroligustilide (3) and 6-butyryl-7-hydroxy-6,7-dihydroligustilide (4) on the basis of the spectral properties. Treatment of ligustilide 6,7-epoxide with hydrochloric acid readily gave 3 and thus 3 was considered to have been formed during the extraction of the plant.
- 社団法人日本薬学会の論文
- 1987-12-25
著者
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三橋 博
Faculty of Pharmaceutical Sciences, Hokkaido University
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三橋 博
Tsumura Institute For Biology And Chemistry
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三橋 博
Faculty Of Pharmaceutical Sciences Hokkaido University
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小林 優
Faculty Of Pharmaceutical Sciencces Hokkaido University
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小林 優
北大薬
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三橋 博
北海道大学薬学部
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