Studies on the Constituents of Asclepiadaceae Plants. LI. Oxidation at the 18-Methyl Group of C/D-cis-Pregnane Type Steroids and ^<13>C-Nuclear Magnetic Resonance Spectra of 18-Oxygenated Pregnanes and Related Compounds

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概要

• 論文の詳細を見る

• Four 18-oxygenated pregnane-type steroids ; 18,20-epoxypregn-5-en-3β-ol acetate (III), 18,20-epoxy-isolineolon cyclic sulfite (VIII), 18,20-epoxy-deacyl condurangogenin C (XVIII), and 18,20-epoxy-20-epideacyl condurangogenin C (XXI) were synthesized, and their structures were established by chemical and spectral studies. A remarkable difference in ^<13>C-nuclear magnetic resonance chemical shifts between 20R-and 20S-hydroxy-C/D-cis-pregnane-type steroids was found.

• 社団法人日本薬学会の論文
• 1982-11-25

著者

• 三橋 博

  Faculty of Pharmaceutical Sciences, Hokkaido University

• 林 紘司

  Faculty of Pharmaceutical Sciences, Hokkaido University

• 木村 雅彦

  Faculty Of Pharmaceutical Sciences Hokkaido University

• 三橋 博

  Research Institute For Biology & Chemistry Tsumura & Co.

• 三橋 博

  Tsumura Institute For Biology And Chemistry

• 三橋 博

  Faculty Of Pharmaceutical Sciences Hokkaido University

• 林 紘司

  Tsumura Central Research Laboratories Tsumura & Co.

• 成田 弘美

  Faculty of Pharmaceutical Sciences, Hokkaido University

• 成田 弘美

  Faculty Of Pharmaceutical Sciences Hokkaido University

• 林 紘司

  Faculty Of Pharmaceutical Sciences Hokkaido University

関連論文

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• Further Investigation of Antitumor Condurangoglycosides with C-18 Oxygenated Aglycone
• Antitumor Active Glycosides from Condurango Cortex
• Studies on the Constituents of Asclepiadaceae Plants. XLIX. Confirmation of the Structures of Antitumor-active Glycosides in Condurango Cortex. Chemical Transformation of the Aglycone Moiety
• Studies on the Constituents of Asclepiadaceae Plants. XLV. On the Components of Metaplexis japonica MAKINO. VI. The Structures of 7-Oxygenated-Pregnane Derivatives
• Components of Metaplexis japonica MAKINO
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• On the Structure of Tomentogenin
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