Studies on the Constituents of Asclepiadaceae Plants. XXXVI. Component of Marsdenia tomentosa DECNE : Structure of Tomentonin, Tomentodin, and Dehydrotomentosin and Difference in the Reactivity between Utendin and Tomentogenin Diesters on Mild Alkaline Hy
スポンサーリンク
概要
- 論文の詳細を見る
Three new polyoxypregnane derivatives, tomentonin (12β-O-dihydrotigloyl-20-O-acetyltomentogenin), tomentodin (12β-O-cinnamoyl-20-O-acetyltomentogenin), and dehydrotomentosin (12β-O-tigloyl-20-O-acetylutendin), were isolated from the stem of Marsdenia tomentosa DECNE. Dehydrotomentosin underwent an internal acyl migration from C-12β-OH to C-20-OH on mild alkaline hydrolysis to afford a monoester, but tomentonin and tomentodin did not. The remarkable difference in the reactivity between toementogenin and utendin diesters on this condition was discussed. Tomentonin is the first example of a tomentogenin derivative with an ester linking of dihydrotiglic acid or 2-methylbutyric acid isolated from Asclepiadaceae plants.
- 社団法人日本薬学会の論文
- 1976-03-25
著者
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三橋 博
Faculty of Pharmaceutical Sciences, Hokkaido University
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林 紘司
Faculty of Pharmaceutical Sciences, Hokkaido University
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三橋 博
Research Institute For Biology & Chemistry Tsumura & Co.
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三橋 博
Faculty Of Pharmaceutical Sciences Hokkaido University
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林 紘司
Tsumura Central Research Laboratories Tsumura & Co.
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瀬戸 秀夫
Faculty of Pharmaceutical Sciences, Hokkaido University
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瀬戸 秀夫
Faculty Of Pharmaceutical Sciences Hokkaido University
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林 紘司
Faculty Of Pharmaceutical Sciences Hokkaido University
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