Studies on Syntheses and Reactions of Methoxypyridazines. II. Methoxylation of 3,4,6-Trichloropyridazine(Organic,Chemical)

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概要

• 論文の詳細を見る

• Methoxylation of 3,4,6-trichloropyridazine (1) with sodium methoxide was investigated in detail. Dimethoxylation of 1 afforded 6-chloro-3,4-dimethoxypyridazine (5) and a molccular complex (M) which is composed of 5 and 3-chloro-4,6-dimethoxypyridazine (6) in a ratio of 1:1. The nature of the complex (M) was examined by thermal and X-ray analyses. The molecular complex (M) was also obtained by monomethoxylation of 3,6-dichloro-4-methoxypyridazine (3) with sodium methoxide.

• 公益社団法人日本薬学会の論文
• 1987-01-25

著者

• 長島 弘

  Gifu Pharmaceutical University

• 正木 幸雄

  Gifu Pharmaceutical University

• 正木 幸雄

  岐阜薬科大学:(現)名城大学薬学部薬化学教室

• 小田 博久

  Gifu Pharmaceutical University

• 鍛冶 健司

  Gifu Pharmaceutical University

• 鵜飼 浄

  Gifu Pharmaceutical University

• 鍛治 健司

  岐阜薬科大学

• Oda Hirohisa

  Gifu Pharmaceutical University

• 鍛冶 健司

  Gifu College Of Pharmacy

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