HIGHLY STEREOSELECTIVE SYNTHESIS AND STRUCTURAL CONFIRMATION OF A FUNGAL METABOLITE, LL-P880β
スポンサーリンク
概要
- 論文の詳細を見る
A fungal metabolite, LL-P880β [6S-(1'S, 2'R-dihydroxypentyl)-4-methoxy-5,6-dihydropyran-2-one] (1), was synthesized unambiguously from diethyl (R, R)-tartrate (3) as a chiral pool via highly stereoselective construction of the C7'-asymmetric carbon of the intermediate 6,8-dioxabicyclo[3.2.1]octane derivative (8a), and the stereochemistry of the C6-chiral center of the metabolite was chemically confirmed as (S).
- 公益社団法人日本薬学会の論文
- 1994-01-15
著者
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正木 幸雄
Gifu Pharmaceutical University
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今枝 稔博
Gifu Pharmaceutical University
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河井 真
Gifu Pharmaceutical University
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