New Index for the Stability of a Type I Collagen Affected by Hydrophobic Environment

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概要

• 論文の詳細を見る

• Effects of hydrophobic environment adjusted by various alcohols on the structural stability of calfskin collagen (CSC) were studied to elucidate the nature of collagen-monomer interaction in adhesion. The stability of CSC in aqueous alcohol solutions was represented by its denaturation temperature, T_d, measured by DSC. The hydrophobicity of the alcohol solutions was quantified with their specific dielectric constants, ε_r, calculated from their concentrations. The effect of each alcohol to stabilize or destabilize CSC was evaluated by the initial slope of each T_d vs. ε_r plot, denoted as -(dT_d/dε_r)_<ini> and termed as stabilization power. Results showed that a hydrophobic environment with a smaller ε_r lowered the stabilization power. Stabilization power ranged from -3 (strong destabilization) for phenol (ε_r = 12) to +0.3 (weak stabilization) for glycerol (ε_r=47). In view of the encouraging results obtained in this study, the new index was therefore helpful in predicting the effects of new dental materials of known ε_r values on the stability of dentinal collagen.

• 日本歯科理工学会の論文

著者

• Takami N

  Department Of Dental Materials Science And Technology Iwate Medical University School Of Dentistry

• 成島 尚之

  Department Of Materials Processing Tohoku University

• Sasaki Kaori

  Division Of Dental Bio-engineering Department Of Pathogenesis And Control Of Oral Diseases Iwate Med

• Nezu T

  Department Of Dental Biomaterials And Technology Iwate Medical University School Of Dentistry

• Taira Masayuki

  Division Of Dental Bio-engineering Department Of Pathogenesis And Control Of Oral Diseases Iwate Med

• Saitoh Setsuo

  Division Of Dental Bio-engineering Department Of Pathogenesis And Control Of Oral Diseases Iwate Med

• ARAKI Yoshima

  Department of Dental Materials Science and Technology, Iwate Medical University School of Dentistry

• NEZU Takashi

  Dental Biomaterials and Technology, Iwate Medical Unversity School of Dentistry

• MORIKAWA Tomohiro

  Fixed Prosthodontics, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University

• SASAKI Kaori

  Dental Biomaterials and Technology, Iwate Medical Unversity School of Dentistry

• SAITOH Setsuo

  Dental Biomaterials and Technology, Iwate Medical Unversity School of Dentistry

• TAIRA Masayuki

  Dental Biomaterials and Technology, Iwate Medical Unversity School of Dentistry

• TERADA Yoshihiro

  Fixed Prosthodontics, Division of Oral Rehabilitation, Faculty of Dental Science, Kyushu University

• ARAKI Yoshima

  Dental Biomaterials and Technology, Iwate Medical Unversity School of Dentistry

• Araki Y

  Department Of Dental Materials Science And Technology Iwate Medical University School Of Dentistry

• Terada Y

  Fixed Prosthodontics Division Of Oral Rehabilitation Faculty Of Dental Science Kyushu University

• Nezu Takashi

  Dental Biomaterials And Technology Iwate Medical Unversity School Of Dentistry

• Morikawa Tomohiro

  Fixed Prosthodontics Division Of Oral Rehabilitation Faculty Of Dental Science Kyushu University

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