Design and Preparation of Universal Anti-PERIOD Antibodies and their Immunoresponses

スポンサーリンク

概要

• 論文の詳細を見る
• 2002-03-01

著者

• Sato S

  Laboratory Of Structure-function Biochemistry Department Of Chemistry Kyushu University

• Takami N

  Department Of Dental Materials Science And Technology Iwate Medical University School Of Dentistry

• ASAI Daisuke

  Faculty and Graduate School of Sciences, Kyushu University

• TOKUNAGA Takatoshi

  Faculty and Graduate School of Sciences, Kyushu University

• MATSUSHIMA Ayami

  Faculty and Graduate School of Sciences, Kyushu University

• SATO Seiji

  Faculty and Graduate School of Sciences, Kyushu University

• CHUMAN Yoshiro

  Faculty and Graduate School of Sciences, Kyushu University

• NOSE Takeru

  Faculty and Graduate School of Sciences, Kyushu University

• TOMINAGA Yoshiya

  Faculty of Science, Fukuoka University

• SHIMOHIGASHI Yasuyuki

  Faculty and Graduate School of Sciences, Kyushu University

• SHIMOHIGASHI Miki

  Faculty of Science, Fukuoka University

• Shimohigashi Miki

  Division Of Biology Faculty Of Science Fukuoka University

• Mohri Shirou

  Department Of Laboratory Animal Science Faculty Of Medical Sciences Kyusyu University

• Sumiyoshi Miho

  九州大学 理学研究院構造機能生化学研究室

• Yoshiya Tominaga

  Laboratory Of Structure-function Biochemistry Department Of Chemistry Faculty And Graduate School Of

• Tominaga Y

  Laboratory Of Structure-function Biochemistry Department Of Chemistry Faculty And Graduate School Of

• Takeru Nose

  Department Of Chemistry Faculty Of Sciences Kyushu University

• Asai D

  Laboratory Of Structure-function Biochemistry Department Of Chemistry Faculty And Graduate School Of

• Chuman Yoshiro

  Division Of Chemistry Graduate School Of Science Hokkaido University

• Takeda Yukimasa

  Laboratory Of Structure-function Biochemistry Department Of Chemistry The Research-education Centre

• Nose Takeru

  Laboratory Of Biochemistry Department Of Chemistry Faculty Of Science Kyushu University

• Shimohigashi Yasuyuki

  Laboratory Of Structure-function Biochemistry Department Of Molecular Chemistry Graduate School Of S

• Tokunaga Takatoshi

  Department Of Chemistry The Research-education Centre Of Risk Science Faculty And Graduate School Of

• Nose Takeru

  Faculty And Graduate School Of Sciences Kyushu University

関連論文

• Splicing Variants of pdf Gene in the Honeybee Apis mellifera
• Gene Expression of Circadian Neuropeptide PDF in Honeybee
• Design and Synthesis of α-Helix Peptide Bonding to Prion Protein N-terminal Octarepeat Domain
• Immunological Evidences of Circadian Neuropeptide PDF Isoform Present at the Lamina Outer Cells and Varicose Network in the Optic Lobes of the Cricket Gryllus bimaculatus
• Identification of Novel Isofoms of the Circadian Neuropeptide PDF in the Silk Moth Bombyx mori and their Expression in Brain
• Triplicate Alternative Splicings that Produce Multiple Variants of the PERIOD Protein in the Silk Moth Bombyx mori by Deletion/Insertion of Peptides
• cDNA Cloning and mRNA Expression of the Circadian Neuropeptide PDF in the Silk Moth Bombyx mori
• Structural Analysis and Identification of Novel Isoforms of the Circadian Clock Gene period in the Silk Moth Bombyx mori(Neurobiology)
• Primary Structure Analyses of Circadian Neuropeptide PDF and Its Precursors in Insect Cicadae and Flies
• Two Distinctly Different Isoforms With/Without Pentapeptide Fragment in the Silk Moth Clock Protein PERIOD
• A CIRCADIAN NEUROPEPTIDE, PDF, IN THE LAST-SUMMER CICADA MEIMUNA OPALIFERA(Physiology)(Proceedings of the Seventy-Third Annual Meeting of the Zoological Society of Japan)
• cDNA Cloning and Nuclear Localization of the Circadian Neuropeptide Designated as Pigment-Dispersing Factor PDF in the Cricket Gryllus bimaculatus
• Design and Preparation of Universal Anti-PERIOD Antibodies and their Immunoresponses
• Structure and Function of Nuclear Localization Signal Peptide Present in Circadian Rhythm Hormone Peptide Precursor
• cDNA Cloning of PDF Peptide Precursors in House Fly and Last Summer Cicada
• Chymotrypsin Inhibition Induced by Side Chain-Side Chain Intramolecular CH/π Interaction in D-Thr-L-Phe Benzylamide
• πHydrogen Bond Between Dipeptide Side Chains as a Structural Essential for Chymotrypsin Inhibition
• Ligand-inducing Conformation Changes in the Estrogen Receptor C-Terminal Tail Moiety and Their Sensing by Polyclonal Antibodies
• Structural Characteristics of Drosophila Estrogen-related Receptor Ligand Binding Domain to Capture the Peptide and Non-peptide Ligands
• LOCALIZATION PROFILES OF ORCADIAN NEUROPEPTIDE PDF IN THE BRAIN OF FLIES, MUSCA DOMESTICA(Physiology,Abstracts of papers presented at the 75^ Annual Meeting of the Zoological Society of Japan)
• Localization Profiles of Circadian Neuropeptide PDF in Brain of the Cricket Gryllus Bimaculatus
• LOCALIZATION PROFILES OF CIRCADIAN NEUROPEPTIDE PDF IN THE BRAIN OF CRICKET, GRYLLUS BIMACULATUS(Physiology,Abstracts of papers presented at the 74^ Annual Meeting of the Zoological Society of Japan)
• α-Helix Peptides for Bio-Panning in the Phage Display Method to Obtain the Antibodies Specific for Conformation Change in Nuclear Receptors
• Highly Sensitive Monoclonal Antibodies to Distinguish Conformational Changes Induced by Endocrine Disrupting Chemicals in the Estrogen Receptor
• Specific Affinity Labeling of Cys60 in the δ Opioid Receptor by Npys-containing Dynorphin A Analog
• Differential Receptor Binding Characteristics of the Phenylalanine Residues at Positions 3-4 of Endomorphin-2
• The Role of Deltorphin II Phenylalanine Residue in Binding to the δ Opioid Receptor
• Exploration of the Role of Phenylalanine in the Thrombin Receptor Tethered-Ligand Peptide by Substitution with a Series of Trifluorophenylalanines
• The Mode of Molecular Interation of Phe-3 of Deltorphin II and Endomorphin 2 in Opioid Receptor Binding
• Receptor Interaction Mode of the Phe-phenyl Group of Opioid Peptides
• Exploration of Universal Cysteines in the Bining Sites of Therr Opioid Receptor Subtypes by Disulfide-Bonding Affinty Labeling with Chemically Activated Thiol-Containing Dynorphin A Analogs
• Affinity Labeling of Opioid Receptor Subtypes by Activated Thiol-containig Dynorphin A Analogs
• Different Roles of Two Consecutive Leucine Residues in a Receptor-Tethered Ligand Peptide (SFLLRNP) in Thrombin Receptor Activation
• The Conformation Change-Sensing Antibodies for Retinoid-Related Orphan Receptor Family
• Differential Receptor Recognition by Dmt-Containing Enkephalin Dimers Cross-Linked by Phenylenediamines
• The Molecular Mechanism of ORL1 Nociceptin Receptor in Activation : Residual Essentials in the Sixth Transmembrane Domain
• Structural Analysis of Excitatory Neuropeptides TEP-1 and TEP-2 Isolated from the Prosobranch Gastopod Thais clavigera
• Optimization of the N-Terminal Group of Ac-RYYRIK-NH_2 as ORL1 Receptor Antagonist
• Structural Profiles for Coacervation of Elastin-derived Polypeptides
• Reversible Affinity Labeling of Opioid Receptors via Disulfide Bonding: Discriminative Labeling of μ and δ Subtypes by Chemically Activated Thiol-Containing Enkephalin Analogs
• Isobutyryl-RYYRIK-NH_2, A Highly Potent Nociceptin Antagonist
• Conformation Change-sensing Assay Using Monoclonal Antibody for N-terminal Octapeptide Repreat Region of Prion Protein
• Structural Characterisitics of the N-Terminal Octapeptide Repeat Region of Prion Protein
• Structural Requirements of the N-terminal Octapeptide Repeat of Prion Protein
• Structural Requirement of the Acyl Group of Ac-RYYRIK-NH_2, an Antagonist of Algesic Neuropeptide Nociceptin
• Structure-Activity Studies on the Nociceptin Peptidic Antagonist Ac-RYYRIK-NH_2
• New Index for the Stability of a Type I Collagen Affected by Hydrophobic Environment
• Synthesis of Pure Antagonist of ORL1 Nociceptin Receptor
• Residual Roles of Hydrophobic Amino Acids in the Fifth Transmembrane Domain of ORL1 Receptor in Its Activation
• Enkephalin Dimers Cross-Linked by Diaminobenzene for Homodimeric Opioid Receptors Expressed in COS-7 Cells
• Continuous Activation of the δ-Opioid Receptor by Affinity Labeling
• Elastin-derived Peptides : Structure, Functions and Mechanisms
• RECEPTOR-MEDIATED BINDING OF ELASTIN-DERIVED HEXAPEPTIDE TO MACROPHAGES INDUCED A GALACTOSUGAR-SENSITIVE CHEMOTAXIS
• Comparison of Chemotactic Activity of Macrophages Induced by Permutations of Elastin-derived Hexapeptide VGVAPG and Pentapeptide VGVPG
• Chemotactic Activation of Macrophages by Elastin Hexapeptide Sequences and Its Signaling Mechanism
• Elastin Peptide-Induced Macrophage Chemotaxis and Its Signal Transduction Pathway
• Involvement of Intracellular Cyclic GMP and Cyclic GMP-Dependent Protein Kinase in α-Elastin-Induced Macrophage Chemotaxis
• Morphologica discrimination of two genetic groups of a Japanese salamander, Hynobius naevius (Amphibia, Caudata)
• MORPHOMETRIC VARIATION OF HYNOBIUS NAEVIUS(Taxonomy and Systematics,Abstracts of papers presented at the 75^ Annual Meeting of the Zoological Society of Japan)
• A COMPARATIVE STUDY ON LARVAL LIFE HISTORIES IN TWO POPULATIONS OF HYNOBIUS BOULENGERI (AMPHIBIA: URODELA) FROM KYUSHU I(Behavior Biology and Ecology,Abstracts of papers presented at the 74^ Annual Meeting of the Zoological Society of Japan)
• GENETIC VARIATION IN HYNOBIUS NAEVIUS(Taxonomy and Systematics,Abstracts of papers presented at the 74^ Annual Meeting of the Zoological Society of Japan)
• Occurrence of two types of Hynobius naevius in northern Kyushu, Japan (Amphibia : Urodela)
• MORPHOLOGICAL AND GENETIC VARIATION OF HYNOBIUS NAEVIUS FROM NORTHERN KYUSHU, JAPAN(Taxonomy and Systematics)(Proceedings of the Seventy-Third Annual Meeting of the Zoological Society of Japan)
• Structural Requirement of Nociceptive Peptide Nociceptin : Structural Importance of C-Terminal Fragment for Receptor Recognition
• Structure-Activity Relationships of a Naturally Occurring Nociceptive Peptide, Nociceptin
• Characteristic Intra- and Intermolecular Interactions of Dipeptide-Chymotrypsin Complex as Specific Structural Essentials for Enzyme Inhibition
• Receptor Binding Site for the Phe-2-Phenyl Group of Thrombin Receptor-Tethered Ligand Peptide : Analyses by Ala/Tyr Mutant Receptors
• Identification of Receptor Binding Site of Nociceptin-14-15, the Residues for High Receptor Potentiation
• Synergistic Potentiation of Nociceptin by Simultaneous Incorporation of Basic Amino Acids at the Consecutive Positions 14-15
• Activity Enhancement by Introduction of Two Different Halogen Atoms into Phe-2-phenyl Group of Thrombin Receptor Tethered-Ligand Analogs
• Edge-to Face CH/π Interaction between Ligand Phe-Phenyl and Receptor Aromatic Group in the Thrombin Receptor Activation
• Highly Potent Peptide Ligands for Thrombin Receptor
• Chemical Syntheses of Phenylalanine Derivatives Containing Halogenated Benzene Ring as Structural Explorers for Elucidation of Molecular Mechanisms of Receptor Interacions
• Desieg and Synthesis of para-Fluorophenylalanine Amide Derivatives as Thrombin Receptor Antagonists
• Structural Essentials for Agonist-Antagonist Actions of Thrombin Receptor Tethered-Ligand
• Importance of Ligand Phe-phenyl Group for Activation of Thrombin Receptor
• Interaction Mode of the Phe-Phenyl Group of Thrombin Receptor-Tethered Ligand SFLLRNP in Receptor Activation
• The Role of Arginine in Thrombin Receptor Tethered-Ligand Peptide in Intramolecular Receptor Binding and Self-Activation
• Effects of Substitution of Hydrophobic Amino Acids by Tryptophan on Receptor Binding and Biological Activity of Neuropeptide Nociceptin
• Effect of HEMA Adsorption on the Stability of Native and Denatured Type I Tendon Collagen
• The Effects of Alcoholic Compounds on the Stability of Type I Collagen Studied by Differential Scanning Calorimetry
• The Effects of Arg→Trp and Lys→Trp Substitutions for Arg-Lys^ Residues in a Superagonist [Arg-Lys^]-Nociceptin on the ORL1 Receptor Binding and Activation
• Molecular Mechanism of α-Helix Peptide That Inhibits Intermolecular Interaction of Prion Protein N-Terminal Tetrarepeat Domain
• Histidines as Structurally Essential Residue for the Delta Opioid Receptor Activation
• Essential Amino Acid Residues in the ORL1 Receptor Transmembrane Domains for Receptor Activation
• Platelet Aggregation Activity of Thrombin Receptor-Tethered Peptide Ligand Containing Free Thiol or Activated SH Group
• Design and Synthesis of para-Fluorophenylalanine Amide Derivatives Containing N-Terminal Thiol as Thrombin Receptor Antagonist
• Conformation Change of α-Helix Peptide for Sensing of Deactivation of Nuclear Receptor : Immunoassay Using Polyclonal Antibody Specific for the C-Terminal α-Helix 12 of Estrogen-Related Receptor γ(ERRγ)
• Hetero-Oligomer Formation of Peptides Derived from Tetramerization Domain in Tumor Suppressor Protein p53
• Leucine-14 of Nociceptin Is a Structural Element in the CH/π Interaction with the Receptor Aromatic Group
• Structural Requirements in Activation of Opioid Receptor-Like ORL1 Receptor by Nociceptin
• Structure-Activity Relationships of Serine Protease Inhibitors with Structural Element Stacking to the Catalytic Residue His-57
• The Effect of Structural Difference between Dipeptide C-Terminal Benzyl Amides and Esters on Chymotrypsin Inhibition
• MITF CONTRIBUTES TO THE DENDRICITY OF MELANOBLASTS IN XENOPUS LAEVIS(Developmental Biology,Abstracts of papers presented at the 75^ Annual Meeting of the Zoological Society of Japan)
• FUNCTIONAL ANALYSES OF MITF GENE IN XENOPUS PIGMENT CELLS(Developmental Biology,Abstracts of papers presented at the 74^ Annual Meeting of the Zoological Society of Japan)
• Peptide Library-Derived Inhibitors of Lipolytic Enzyme Phospholipase A_2
• Three Dimensional Crystal Structure of Dipeptide-Chymotrypsin Complex Revealed a Novel Inhibitory Interaction
• Apis pdf gene expresses in circadian manner
• A Characteristic Difference among GroEL Homologs from Intracellular Symbionts of Closely-Interrelated Species of Aphid
• A Circadian Neuropeptide PDF in the Honeybee, Apis mellifera : cDNA Cloning and Expression of mRNA

もっと見る 閉じる

スポンサーリンク