Lignans from Arctium lappa and Their Inhibition of LPS-Induced Nitric Oxide Production
スポンサーリンク
概要
- 論文の詳細を見る
A new butyrolactone sesquilignan, isolappaol C (1), together with four known lignans, lappaol C (2), lappaol D (3), lappaol F (4), and diarctigenin (5), were isolated from the methanolic extract of the seeds from the Arctium lappa plant. The structure of isolappaol C (1) was determined by spectral analysis including 1D- and 2D-NMR. All the isolates were evaluated for their inhibitory effects on the LPS-induced nitric oxide production using murine macrophage RAW264.7 cells. Lappaol F (4) and diarctigenin (5) strongly inhibited NO production in the LPS-stimulated RAW264.7 cells with IC_<50> values of 9.5 and 9.6μM, respectively.
- 公益社団法人日本薬学会の論文
- 2007-01-01
著者
-
Hong Seong
College Of Pharmacy Chungbuk National University:division Of Biotechnology College Of Life Sciences
-
Hong S
Chungbuk National Univ. Cheongju Kor
-
Park So
College Of Pharmacy Chungbuk National University
-
Hwang Bang
College Of Pharmacy Chungbuk National University
-
HAN Xiang
College of Pharmacy, Chungbuk National University
-
HWANG Ji
College of Pharmacy, Chungbuk National University
-
LEE Dongho
Division of Biotechnology, College of Life Sciences and Biotechnology, Korea University
-
Han Xiang
College Of Pharmacy Chungbuk National University
-
RO Jai
College of Pharmacy, Chungbuk National University
-
Ro Jai
College Of Pharmacy Chungbuk National University
-
Hwang Ji
College Of Pharmacy Chungbuk National University
-
Lee Dongho
Division Of Biotechnology College Of Life Sciences And Biotechnology Korea University
-
Lee Dongho
Anticancer Research Laboratory Korea Research Institute Of Bioscience And Biotechnology
-
Hwang Bang
Coll. Of Pharmacy Chungbuk National Univ.
-
Han Xiang
College Of Natural Resources And Life Science Bk21 Center For Silver-bio Industrialization Dong-a Un
関連論文
- Inhibitory Effects of Coumarins from the Stem Barks of Fraxinus rhynchophylla on Adipocyte Differentiation in 3T3-L1 Cells
- Quinolone Alkaloids with Inhibitory Activity against Nuclear Factor of Activated T Cells from the Fruits of Evodia rutaecarpa(Pharmacognosy)
- Melampolides from the Leaves of Smallanthus sonchifolius and Their Inhibitory Activity of LPS-Induced Nitric Oxide Production
- Inhibition of Cell Growth and Induction of Apoptosis via Inactivation of NF-κB by a Sulfurcompound Isolated From Garlic in Human Colon Cancer Cells
- Inhibitory effect of a traditional Chinese formulation, Hyul-Tong-Ryung, on PMA-induced MMP-9 expression in MCF-7 human breast carcinoma cells
- Licorice Extract Does Not Impair the Male Reproductive Function of Rats
- Two New Stereoisomers of Tetrahydrofuranoid Lignans from the Flower Buds of Magnolia fargesii
- Delphinidin Ameliorates Beta-Amyloid-Induced Neurotoxicity by Inhibiting Calcium Influx and Tau Hyperphosphorylation
- Lignans from Arctium lappa and Their Inhibition of LPS-Induced Nitric Oxide Production
- Piperine from the Fruits of Piper longum with Inhibitory Effect on Monoamine Oxidase and Antidepressant-Like Activity
- 1-Methyl-2-undecyl-4(1H)-quinolone as an Irreversible and Selective Inhibitor of Type B Monoamine Oxidase
- Anxiolytic-Like Effects of Ginsenosides on the Elevated Plus-Maze Model in Mice(Pharmacology)
- Anti-Inflammatory Effects of an Ethanol Extract of Angelica gigas in a Carrageenan-Air Pouch Inflammation Model
- Delphinidin Ameliorates Beta-Amyloid-Induced Neurotoxicity by Inhibiting Calcium Influx and Tau Hyperphosphorylation
- Cytotoxic 6-Alkylsalicylic Acids from the Endophytic Streptomyces laceyi
- Antifibrotic activity of coumarins from Cnidium monnieri fruits in HSC-T6 hepatic stellate cells
- New non-quinone geldanamycin analogs from genetically engineered Streptomyces hygroscopicus