Macroscopic Findings and Mucous Phenotypes of Early Gastric Depressed Type Carcinomas
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概要
- 論文の詳細を見る
We studied the macroscopic features of differentiated-type gastric carcinomas to discern mucin phenotypes using 50 cases (54 lesions) of early gastric depressed type carcinomas, employing MUC5AC, MUC6, MUC2 and CD10 immunostains. We identified the G-phenotype (gastric phenotype) in 12 lesions, the gastrointestinal phenotype in 26 lesions, and the intestinal phenotype in 16 lesions. Carcinomas with the gastric phenotype revealed a significantly higher incidence of discolored surface (58.3%) than those with the intestinal phenotype (18.7%) (p<0.05). Carcinomas with the gastric phenotype also demonstrated a significantly higher incidence of non-wavy tumor margins (83.3%); those with the intestinal phenotype had only an 18.7% incidence of non-wavy tumor margins (p<0.01). No difference in the clarity of the marginal outline was found among the mucous phenotypes. The mucosal heights measured under a microscope revealed that the shallowest depressions among the nuclear-margin group were associated with gastric phenotype lesions.
- 新潟大学の論文
著者
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Watanabe Gen
新潟大学 医歯学総合研究科消化器･一般外科学分野
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Watanabe Gen
Divisions Of Molecular And Diagnostic Pathology Graduate School Of Medical And Dental Sciences Niiga
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Ajioka Y
Divisions Of Molecular And Diagnostic Pathology Graduate School Of Medical And Dental Sciences Niiga
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Ajioka Yoichi
獨協医科大学 病理学人体分子
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Ajioka Yoichi
新潟大学 医歯学総合研究科消化器･一般外科学分野
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Ajioka Yoichi
Division Of Molecular Diagnostic Pathology Niigata University Medical And Dental Hospital
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Ajioka Yoichi
新潟大学 医歯総合研究 遺伝子制御
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Ajioka Yoichi
新潟大学 医歯学総合研究科消化器内科学
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Nishikura Ken
Division of Molecular and Diagnostic Pathology, Department of Molecular Genetics, Graduate School of
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Nakamura Kazuto
Department Of Gastroenterology And Hepatology Tokyo Medical University
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Watanabe Gen
Division Of Molecular And Diagnostic Pathology Department Of Molecular Genetics Niigata University
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Nishikura Ken
Divisions Of Molecular And Diagnostic Pathology Graduate School Of Medical And Dental Sciences Niiga
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Nishikura Ken
First Department Of Pathology Niigata University School Of Medicine
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Nishikura Ken
Division Of Molecular And Diagnostic Pathology Niigata University Graduate School Of Medical And Den
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Ajioka Yoichi
Division Of Molecular And Functional Pathology Niigata University
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Yoichi Ajioka
The First Department Of Pathology Niigata University Schoolof Medicine
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BABA Youichiro
Division of Molecular and Diagnostic Pathology, Department of Molecular Genetics, Niigata University
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Ajioka Youichi
Divison Of Molecular And Diagnostic Pathology Niigata University
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HIGUCHI Kiyotaka
Division of Molecular and Diagnostic Pathology, Department of Molecular Genetics
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Watanabe Hidenobu
Division Of Molecular And Functional Pathology Department Of Cellular Function Graduate School Of Me
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Nishlkura Ken
Division Of Molecular And Functional Pathology Niigata University
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Ajioka Y
Division Of Molecular And Functional Pathology Department Of Cellular Function Graduate School Of Me
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Higuchi Kiyotaka
Division Of Molecular And Diagnostic Pathology Department Of Molecular Genetics:department Of Radiol
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Ajioka Yoichi
Division Of Molecular And Diagnostic Pathology Department Of Molecular Genetics Graduate School Of M
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AJIOKA Yoichi
Niigata University Graduate School of Medical and Dental Sciences
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Ajioka Yoichi
Division Of Cardiology Niigata University Graduate School Of Medical And Dental Sciences
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Watanabe Gen
Division of Molecular and Diagnostic Pathology, Department of Molecular Genetics, Graduate School of Medical and Dental Sciences, Niigata University
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