抗がん剤用安全取扱器具PhaSeal^[○!R] systemの操作性の評価

概要

論文の詳細を見る
Most antineoplastic agents used in chemotherapy are cytotoxic and could damage the health of medical staff when they are exposed to them. To counter this risk, a safety cabinet is commonly used. Since such cabinets have been reported to be lacking, the PhaSeal^[○!R] system (PS-s, a sealed-type safety device) was developed for use with the safety cabinet, and has been reported to be effective in studies done in Europe and the US. We tested the PS-s at a medical institution in Japan with regard to suitability and easy of operation. In the testing, the PS-s was compared with the conventional system (C-s) as regards preparation time using ten pharmacists and ten nurses as subjects. Afterwards, a questionnaire survey on the test results was conducted. The total preparation time required for C-s was 42.6±11.15 seconds and that for PS-s was significantly longer at 63.3±14.99 seconds (p<0.01). The time required for aspiration of drug from the vial was 27.2±9.08 seconds for C-s and 17.7±5.53 seconds for PS-s, which was significantly shorter (p<0.01). The questionnaire survey results indicated that PS-s was much safer to use for medical professionals but their opinions were divided as to whether it was easier to operate or not. We concluded that PS-s would be useful in the preparation of cytotoxic anticancer agents if medical staff could become more familiar with its operating procedure.
日本医療薬学会の論文
2006-12-10