Effects of Tobacco Smoking on Frontal Lobe Function in Normal Healthy Volunteer
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概要
- 論文の詳細を見る
To evaluate the efficacy of tobacco smoking on working memory of healthy normal volunteer, Computer-based-revised Keio type Wisconsin Card Sorting Test (WCST) was administered and analyzed. Thirteen normal healthy nonsmokers and 10 normal healthy smokers had WCST, however, for smoker group WCST was administered immediately after tobacco smoking (1mg of nicotine and 12mg of tar). As the results, smoker group showed higher score in both Number of response card until the first category achieved (NUCA) and Perseverative errors of Nelson (PEN) (P<0.05). These results indicate that smokers have difficulty in changing and maintaining mental set, which means decrease in flexibility and adaptability of attention. These data suggest that tobacco smoking may have acute effect on working memory of brain.
- 獨協医科大学の論文
- 2005-07-25
著者
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HIRATA KOICHI
Department of Gastrointestinal Surgery and Oncological Surgery, Sapporo Medical University School of
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Akiyama Kazufumi
Department Of Psychiatry
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Akiyama Kazufumi
Department Of Chemistry Faculty Of Science Josai University
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Matsuda Naoto
Dokkyo University School of Medicine
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Yuki Tsumugi
Dokkyo University School of Medicine
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Hirata Koichi
Department Of Neurology
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Hirata Koichi
Department Of Gastrointestinal Surgery And Oncological Surgery Sapporo Medical University School Of
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Hirata Kouichi
Department of Neurology, Cenrer of Sleep Medicine, Dokkyo Medical University School of Medicine
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Hirata Koichi
Department of Chemistry, Faculty of Science, Osaka University
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