EFFECTS OF BICYCLE ERGOMETER EXERCISE AND PGE_1 INJECTION FOR PATIENTS WITH INTERMITTENT CLAUDICATION(Proceedings of The 8^<th> Asian Federation of Sports Medicine Congress 2005 Tokyo)

概要

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The purpose of this study was to clarify the effects of bicycle ergometer training and prostaglandin E_1 (PGE_1) for patients with intermittent claudication. Subjects were divided into four groups: the medication group (M), the PGE_1 group (P), the exercise group (E) and the PGE_1 and exercise group (PE). The P group was injected with 10μg of PGE_1, the E group performed bicycle ergometer exercise 3 times a week for 6 weeks, and the PE group was injected with PGE_1 and performed exercises. The maximal walking distance (MWD) was evaluated by a treadmill test. Muscle oxygenation level was measured by near-infrared spectroscopy and recovery half time (T_<1/2>) was calculated. MWD was significantly improved for P (142%), E (216%) and PE (240%) groups. T<1/2> was significantly improved in the E and PE groups. This study indicates that improvement of MWD was a result of development of muscle perfusion in lower limbs and PGE_1 injection may support exercise therapy.
2006-10-01