The Isoelectric Focusing Pattern of Desialylated α1-antichymotrypsin of Heterozygous α1-antichymotrypsin Deficiency and of Acute Phase Plasma
スポンサーリンク
概要
- 論文の詳細を見る
In an attempt to find a molecular marker for the putative abnormal allele in heterozygous α1-antichymotrypsin (ACT) deficiency (a rare trait associated with early emphysema, childhood asthma and chronic "cryptogenic" liver disease) the isoelectric focusing pattern of neuraminidase treated plasma samples from subjects of ACT deficiency families as well as acute phase plasma were compared. There was no difference in the isoform pattern of plasma from ACT deficiency heterozygotes, normal subjects or patients with acute phase response. However, in acute phase plasma there was a disproportional increase in two isoforms, one of which conceivably may be used to mark the early phase of the acute phase response.
- 東海大学の論文
著者
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Tsuda Michio
Department of Medical Education Tokai University, School of Medicine
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Tsuda Michio
Department Of Biochemistry School Of Medicine Tokai University
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YAMAMURA Masaichi
Department of Molecular Life Science, Tokai University School of Medicine
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Tamura M
Univ. Tsukuba Ibaraki
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KAMIGUCHI Hiroshi
Division of Biochemistry, Interdepartmental Laboratory, School of Medicine, Tokai University
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LINDMARK Bertil
Department of Medicine, Malmo General Hospital
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Yamamura Masaichi
Department Of Biochemistry School Of Medicine Tokai University
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Kamiguchi Hiroshi
Division Of Biochemistry Interdepartment Laboratory School Of Medicine Tokai University
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Kamiguchi Hiroshi
Division Of Biochemistry Interdepartment Laboratory
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Lindmark Bertil
Department Of Medicine Malmo General Hospital
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