脳幹部神経細胞体内のエオジン好性小顆粒について

概要

論文の詳細を見る
Recently several workers have mentioned intracellular eosinophilic fine granules (EFG) in nerve cells. KATO and TAKAYAMA described the EFG of the substantia nigra and locus caeruleus as the nonspecific findings in several diagnoses. On the other hand similar EFG in the anterior horn cells of patients with amyotrophic lateral sclerosis have been observed by BUNINA. However distribution, frequency, and grade of those EFG in various parts of barin have not been systematically studied. In this paper 88 medicolegal autopsy cases were studied with the EFG of the endbrain, interbrain, midbrain, pons, medulla oblongata and cerebellum by light microscopy. Additionally partial EFG were also examined histochemically and electron microscopically. The materials comprized asphyxia (34 cases), coronary artery disease (14 cases), poisoning (10 cases), bleeding (10 cases), cerebro vascular disease (9 cases) and other causes of death (11 cases). The results obtained were summarized as follows: 1. The EFG could not be observed in the examined brains of neonates. 2. The EFG appeared initially in pons (about 6 months after birth), later in midbrain (about 1 year of age) and lastly in interbrain and medulla oblongata (about 5 years of age). 3. Correlations could be scarcely found between the presence of the EFG and age (over 10 years of age), sex or cause of death. 4. The EFG seemed to be different from lipofuscin or neuromelanin by histochemical and electron microscopical findings.
北里大学の論文
1978-08-31

脳幹部神経細胞体内のエオジン好性小顆粒について

スポンサーリンク

概要

著者

関連論文

スポンサーリンク