Effects of Changes in Chamber Geometry by Chronic Pressure-Overload on Wall Stress and Strain as Studied in the Potassium-Arrested Canine Left Ventricle
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概要
- 論文の詳細を見る
We studied defferences in stress and strain distributions within the left ventricular wall between the normal heart and the pressure-overload hypertrophied heart. Diastolic left ventricular pressurevolume (P-V) relations of both ventricles were recorded using isolated potassium-arrested heart preparations. The P-V relations thus obtained were analyzed based on the large deformation theory. In this study, the left ventricle was assumed to be a thick spherical shell and its wall was assumed to consist of a homogeneous elastic material. In the hypertrophied heart, the wall stress at every layer of the diastolic left ventricle was smaller than that of the normal heart except in the close vicinity of the endocardial surface when compared at the same left ventricular pressure. Therefore, we concluded that the occurrence of concentric hypertrophy under pressure-overload may contribute in reducing the preload of the hypertrophied ventricle. It was thus suggested that the preload reserve of the pressure-overload heart exceeded that of the normal heart.
- 東海大学の論文
著者
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Suzuki Norio
College Of Med. Science Tohoku Univ.
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Nakamura Toshio
Dept. Of Int. Med. St. Marianna Univ. Yokohama Seibu Hospital
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Arai Shigeru
Dept. 1 of Path, Yamagata Univ. Sch. of Med.
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NAKAMURA Toshio
Department of Internal Medicine 1, Tokai University School of Medicine.
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ABE Hiroyuki
Faculty of Engineering, Tohoku University.
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KIMURA Teruo
Department of Medicine, Research Institute for Chest Diseases and Cancer, Tohoku University.
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MOTOMIYA Masakichi
Department of Medicine, Research Institute for Chest Diseases and Cancer, Tohoku University.
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ARAI Shigeru
Department of Pathology 1, Yamagata University School of Medicine.
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ASOO Noboru
Department of Medicine, Research Institute for Chest Diseases and Cancer, Tohoku University
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Suzuki Norio
Coll Of Med Tohoku Univ Sch Of Med
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Arai Shigeru
Dept. 1 Of Path Yamagata Univ. Sch. Of Med.
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Motomiya Masakichi
Dept. Of Int. Med. Res. Inst. For Chest Diseases & Cancer Tohoku Univ.
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Motomiya Masakichi
Department Of Medicine Sendai Teishin Hospital
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Aso Noboru
Department Of Medicine Research Institute For Chest Diseases And Cancer Tohoku University
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Kimura Teruo
Dept. Of Int. Med. Res. Inst. For Chest Diseases & Cancer Tohoku Univ.
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Abe Hiroyuki
Faculty Of Engineering Tohoku University.
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Abe Hiroyuki
Faculty Of Engineering Tohoku University
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Nakamura Toshio
Department Of Computer And Mathematical Sciences Graduate School Of Information Sciences Tohoku Univ
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Arai Shigeru
Department Of Applied Physics Faculty Of Engineering University Of Tokyo
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Kimura T
Department Of Mechanical Engineering Fukui University
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Kimura Teruo
Department Of Integrated Neuroscience Brain Research Institute University Of Niigata
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Nakamura T
東海大学 第1内科
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Nakamura Toshio
Department Of Biophysics Neuroinformation Research Institute School Of Medicine Kanazawa University
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Nakamura Toshio
Dept. Physiol. Tokai Univ. Sch. Med.
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Kimura Teruo
Department Of Advanced Fibro-science Kyoto Institute Of Technology
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