Evaluation of Efficacy of an Automated Single-Voxel Proton MRS Algorithm on a 3T System

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概要

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• Purpose: To evaluate the efficacy of a fully automatic, single-voxel, proton MR spectroscopy algorithm on a 3.0T MR system.Methods: The PROBE/SVQ algorithm (GE Medical Systems) was evaluated on a General Electric (GE) Signa LX-3T system. Ten normal volunteers (female, 21.1±2.0 years old) participated in the study. Nine representative regions of interest were examined, namely, right and left frontal white matter; right and left parietal white matter; right and left basal ganglia; right and left dentate nucleus; and pons.Results: The mean coefficients of variation in all regions for the N-acetyl-aspartate to creatine ratio (NAA/Cr), choline to creatine ratio (Cho/Cr), and choline to N-acetyl-aspartate ratio (Cho/NAA) were 10.2±2.4%, 11.4±3.2% and 12.6±1.4%, respectively.Conclusion: A fully automated spectroscopic examination under clinical setting utilizing the PROBE/SVQ algorithm appears to be a reliable method, extending the window of routine clinical assessment of brain metabolism.

• 日本磁気共鳴医学会の論文
• 2002-07-01

著者

• KIMURA Teruo

  Department of Medicine, Research Institute for Chest Diseases and Cancer, Tohoku University.

• KWEE Ingrid

  Department of Neurology, University of California

• NAKADA Tsutomu

  Center for Integrated Human Brain Science, Brain Research Institute, University of Niigata

• Kwee Ingrid

  Department Of Neurology University Of California

• NAKADA Tsutomu

  Department of Oriental Medicine, School of Medicine, Keio University

• MATSUZAWA Hitoshi

  Department of Neurosurgery, Hokkaido University School of Medicine, and Sapporo Azabu Neurosurgical

• Nakada Tsutomu

  Center For Integrated Brain Science Brain Research Institute University Of Niigata

• Nakada Tsutomu

  Department Of Biological Sciences Tokyo Institute Of Technology

• Matsuda Tsuyoshi

  Application Research Department Ge Yokogawa Medical Systems Ltd.

• OHKUBO Masaki

  Department of Radiological Technology, School of Health Sciences, Faculty of Medicine, University of

• Ohkubo Masaki

  Department Of Radiological Technology School Of Health Sciences Faculty Of Medicine University Of Ni

• Ohkubo Masaki

  Department Of Radiological Technology School Of Health Sciences Faculty Of Medicine Niigata Universi

• MATSUZAWA Hitoshi

  Center for Integrated Brain Science, Brain Research Institute, University of Niigata

• Matsuzawa Hitoshi

  Center For Integrated Brain Science Brain Research Institute University Of Niigata

• Matsuzawa Hitoshi

  Department Of Neurosurgery Hokkaido University School Of Medicine And Sapporo Azabu Neurosurgical Ho

• Kimura Teruo

  Department Of Integrated Neuroscience Brain Research Institute University Of Niigata

• Kimura Teruo

  Department Of Advanced Fibro-science Kyoto Institute Of Technology

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