アルツハイマー型痴呆者における上肢機能と知的機能、日常生活動作との関係

概要

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Dementia begins insidiously progressive intellectual deterioration. Motor function of the senile dementia of the Alzheimer type (SDAT) patients is sometimes observed to be disturbed to some extent. The relationship of hand function to cognitive disturbances, activities of daily living (ADL) in the SDAT patients were investigated. Their function of upper extremity can be reliably measured by Simple Test for Evaluation of Hand Function (STEP). They were evaluated by Mini-Mental State Examination (MMSE) and Raven's Coloured Progressive Matrices (RCPM). They were also evaluated by ADL test of Barthel Index (BI). Thirty-seven subjects were classified into four groups (normal, mildly, moderately, and severely impaired) based on MMSE scores. Motor speed of upper extremities in severe SDAT groups was significantly slower than that of the control group (p<0.001), but that in mild and moderate SDAT groups were not significantly slower than that of the control group. Cognitive function and ADL in moderate and severe SDAT groups were significantly lower than that of the control group (p<0.001), but that in mild SDAT group was not significantly lower than that of the control group. Although cognitive function and ADL were impaired in the moderate SDAT groups, motor function is still preserved even in moderate stages of the condition.
神戸大学の論文