Deformability in Hardened and Normal Erythrocytes during Sedimentation Process

概要

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In order to clarify the effect of erythrocyte deformability on the sedimentation rate, we have measured the sedimentation curve of hardened swine erythrocytes in a saline solution and have compared it with that of normal erythrocytes. The observed length of the medium along the vessel was linearly proportional to the sedimentation period. The initial slope υ of the sedimentation curve decreased with increase in the volume fraction of erythrocytes. Sedimentation rate υ of hardened erythrocytes was comparable to that of normal ones at low volume fractions, but was smaller at high volume fractions. These experimental data were analyzed with a theoretical formula developed by Oka Biorheology 22 (1985) 315, resulting in a deformability factor of f=0.99 for hardened erythrocytes. This value of f is reasonable for such rigid cells and is much larger than the value for normal erythrocytes, approx. 2/3.
社団法人応用物理学会の論文
1993-03-15