Erythrocyte Sedimentation in Plasma Observed under Microscope

概要

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In order to elucidate the mechanism of erythrocyte sedimentation in plasma, we have measured the concentration distribution of erythrocytes in a sedimentation vessel using a newly developed image analyzing system. As time passes, erythrocyte-poor domains are formed in the suspension column. The total number of domains as well as the size of each domain, was evaluated by a series of analyses, setting up various volume fraction thresholds Hr for the domain. The total number of domains initially increases, reaches a maximum just when the interface roughness of the suspension column is maximum, and then decreases gradually. These characteristic behaviors are found in a wide range of Hr from 0.03 to 0.46. These results suggest that the sigmoidal erythrocyte sedimentation curve can be explained by an effective upflow of plasma through the erythrocyte-poor domain which is produced by aggregation of erythrocytes. Other previous experimental reports are also discussed on the basis of our results.
社団法人応用物理学会の論文
1994-04-15