Reaction Products of 4-Aza- and 4-Methyl-4-azacholest-5-en-3-one with Nitrous Acid

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概要

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• Reaction of sodium nitrite with enamine-type lactams (II and IX) was studied. The products were identified as oxime (III), ketone (IV and V), and nitrile (VI) from II and oxime (X), nitrimine (XI), and nitrile (XII) from IX. These were formed by initial attack of the nitroso ion on C-6 followed by concurrent fragmentation or hydrolysis. Formation of N-nitroso derivatives or deaza compounds was not observed.

• 公益社団法人日本薬学会の論文
• 1972-04-25

著者

• 三橋 博

  Faculty of Pharmaceutical Sciences, Hokkaido University

• 三橋 博

  Tsumura Institute For Biology And Chemistry

• 三橋 博

  Faculty Of Pharmaceutical Sciences Hokkaido University

• 小林 優

  Faculty Of Pharmaceutical Sciencces Hokkaido University

• 古瀬 英雄

  Faculty of Pharmaceutical Sciences, Hokkaido University

• 古瀬 英雄

  Faculty Of Pharmaceutical Sciences Hokkaido University

関連論文

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• Components of Metaplexis japonica MAKINO
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• Studies on the Constituents of Asclepiadaceae Plants. XIX. Components of Metaplexis japonica MAKINO. IV.
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• Studies on the Constituents of Asclepiadaceae Plants. XV. On the Components of Metaplexis japonica MAKINO. II
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