粉粒体の圧縮成型に関する研究(第4報) : 繰返し圧縮に関する2,3の考察

概要

論文の詳細を見る
As one of the methods for effectively carrying out the compression of powder granules (granular powders), repeated compression is reported. In order to examine the effect of compressive force, amount of charge, particle, size and addition of a lubricant agent on compression, experiments were carried out with substances showing considerable difference in compression characteristics, i.e., calcium citrate tetrahydrate, L-ascorbic acid, microcrystal-cellulose, and spherical granules. As a concerted phenomenon that occurs in repeated compression, a model given in Fig. 7 and 8 was presented, and equations (1) and (2) were proposed as the empirical formula for repeated compression characteristics. Measurement of repeated compression characteristics suggested some facts about internal structure of compression-molded substances, and made it possible to presume approximately the necessity for lubricant agent and its amount.
公益社団法人日本薬学会の論文
1969-08-25