和漢薬作用に関する薬学的基礎研究(第7報) : 民間薬方剤"六神丸"構成生薬の心臓機能における複合作用について

概要

論文の詳細を見る
In order to clarify the action of a proprietary drug "Rokushingan"on cardiac function, conjugation action of its componental crude drugs (Bufonis, Bezoar, Moschus, Borneo-Camphora, Realgar, and pearl powder) was examined. All these crude drugs effected contraction of the coronary vascular system, while Bufonis alone effects selective contraction of the excised heart, indicating that Bufonis is responsible for the principal action of Rokusingan. Conjugation effect of the componental crude drugs was examined with the papillary Muscles of a cat and a rabbit, and the contraction of papillary muscles by Bufonis was found to be inhibited by the combined use of Moschus, Bezoar, and Realgar. This fact suggests that the crude drugs contained in Rokusingan show the effect not appreciable by each of them alone but by their conjugation effect.
公益社団法人日本薬学会の論文
1968-02-25