和漢薬作用に関する薬学的基礎研究(第10報) : 六神丸構成生薬の血管透過性阻止作用における複合効果について

概要

論文の詳細を見る
Inhibitory effect of Rokusingan and crude drugs contained in it was examined with dd-strain albino mice on the capillary permeability stimulated with acetic acid. The potency of Rokusingan was comparable to that of rutin and each of Bezoar, Moschus, and Bufonis had higher activity than rutin. Combination of these three crude drugs showed synergistic effect and this combined action was antagonized by other crude drugs, such as Realgar, Pearl, and Borneo-camphora. All the components contained in Bezoar, sodium cholate, deoxycholate, and the smooth muscle contracting substances showed higher activity than bezoar. It was concluded from these results that the synergistic effect of Rokusingan is recognized in capillary permeability.
公益社団法人日本薬学会の論文
1968-11-25