水銀化合物の環境衛生学的研究(第3報)一般母体における水銀化合物の胎盤透過と胎児への蓄積について

概要

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In order to study the placental transfer of mercury compounds and their accumulation in fetus in normal maternal body, total mercury and methylmercury contents in maternal blood, placenta, and umbilical cord blood were examined in 89 women after normal delivery, living in Nagoya city, and the following results were obtained. 1) In methylmercury content, there was a highly significant correlation between maternal blood and placenta but highly significant correlation was not found between them for total mercury content. 2) There was highly significant correlation in methylmercury content between placenta and umbilical cord blood. 3) There was a highly significant correlation in total mercury and methylmercury contents in blood, between maternal blood and umbilical cord blood. It was concluded that mercury compounds, especially methylmercury compounds, transferred through the placenta to fetus and accumlated there, and that higher intake of mercury compounds into the maternal body resulted in the higher mercury content in umbilical cord blood.
公益社団法人日本薬学会の論文
1976-12-31