Inhibition of Purified Human Sucrase and Isomaltase by Ethanolamine Derivatives
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概要
- 論文の詳細を見る
Sucrase-isomaltase complex was purified from human intestinal mucosa. Immunostaining shows that sucrase-isomaltase is confined to the area of the striated cell borders of human small intestinal absorptive cells of the villus. Inhibition of sucrase and isomaltase activity by ethanolamine derivatives was investigated. Tris inhibits both types of enzyme activity and is the strongest inhibitor of the ethanolamine derivatives investigated. Bis-Tris inhibited sucrase more than isomaltase. On the other hand, mono-, di- and tri-ethanolamine were weak inhibitors of sucrase but not isomaltase.
- 社団法人日本薬学会の論文
- 1996-03-15
著者
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平野 和行
岐阜薬科大学 薬剤学
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TATEMATSU Masae
Laboratory of Pathology, Aichi Cancer Center Research Institute
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HIRANO Kazuyuki
Department ofPharmaceutics, Glfu Pharmaceutical University
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USAMI Yoshiko
岐阜薬科大学薬剤学教室
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ADACHI Tetsuo
岐阜薬科大学薬剤学教室
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平野 和行
岐阜薬科大学 薬剤学教室
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Adachi T
Laboratory Of Clinical Pharmaceutics Gifu Pharmaceutical University
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Adachi Tetsuo
Department Of Pharmaceutics Gifu Pharmaceutical University
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Adachi Tetsuo
Department Of Clinical Pharmaceutics Gifu Pharmaceutical University
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Usami Y
Nagoya National Hospital (tokai Area Central Hospital For Aids Treatment And Res.) Aichi Jpn
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USAMI Yoshiko
Department of Pharmaceutics, Gifu Pharmaceutical University
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KANO Toshiko
Department of Pharmaceutics, Gifu Pharmaceutical University
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Tatematsu Masae
Laboratory Of Pathology Aichi Cancer Center Research Institute
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Hirano Kazuyuki
Department Of Material Chemistry Graduate School Of Engineering Kyoto University
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Hirano Kazuyuki
Department Of Pharmaceutcs Gifu Pharmaceutical University
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Kizu Hiroto
Department Of Radiology Kanazawa University Hospital
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HIRANO Kazuyuki
Department of Clinical Chemistry School of Health Sciences, Fujita Health University
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Tatematsu Masae
Laboratory of Oncological Pathology, Aichi Cancer Center Research Institute
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