Cyclooxygenase-2 Inhibitory 1,4-Naphthoquinones from Impatiens balsamina L.
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概要
- 論文の詳細を見る
Significant selective cyclooxygenase-2 (COX-2) inhibitory activities were observed for two new 1,4-naphthoquinone sodium salts, sodium 3-hydroxide-2{[sodium 3-hydroxide-1,4-dioxo(2-naphthyl)]ethyl}naphthalene-1,4-dione (impatienolate) (1) and sodium 2-hydroxide-3-(2-hydroxyethyl)naphthalene-1,4-dione (balsaminolate) (2), which were isolated from the corolla of Impatiens balsamina L. (Balsaminaceae). Their structures were elucidated by spectral techniques. Our results offer evidence supporting the use of I. balsamina L. to treat articular rheumatism, pain, and swelling.
- 社団法人日本薬学会の論文
- 2002-05-01
著者
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奥 尚枝
武庫川女大薬
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石黒 京子
武庫川女大薬
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石黒 京子
武庫川女子大学生薬学研究室
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Oku H
School Of Pharmaceutical Sciences Mukogawa Women's University
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Oku Hisae
Mukogawa Women's University School Of Pharmaceutical Sciences
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Ishiguro Kyoko
Mukogawa Women's University School of Pharmaceutical Sciences
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Okamura Haruki
兵庫医科大学 病理学第一講座
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Ishiguro Kyoko
School Of Pharmacy And Pharmaceutical Sciences Mukogawa Women's Univ.
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石黒 京子
Mukogawa Women's Univ. Nishinomiya Jpn
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石黒 京子
武庫川女子大学 薬
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Ishiguro Kyoko
Mukogawa Women's University School Of Pharmaceutical Sciences
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Ishiguro Kyoko
Faculty Of Pharmaceutical Sciences Mukogawa Women's University:pharmaceutical Research Center K
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Oku Hisae
武庫川女子大学 薬学研究科
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Ito K
Faculty Of Pharmaceutical Sciences Mukogawa Women's University:pharmaceutical Research Center K
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