Effects of Two Saponins Extracted from the Polygonatum Zanlanscianense Pamp on the Human Leukemia (HL-60) Cells
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概要
- 論文の詳細を見る
Two saponins, methyl protodioscin and dioscin, were extracted from the root of Polygonatum Zanlanscianense Pamp. One of them, dioscin exerted significant inhibitory effects on the growth of the human leukemia cell HL-60, inducing differentiation and apoptosis. HL60 cells were induced mainly along the granulocytic lineage. In addition, we have found that dioscin affects many cancer cells. These studies may have important significance in treating related cancers.
- 社団法人日本薬学会の論文
- 2001-02-01
著者
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Wang Z
Department Of Biological Sciences And Biotechnology Tsinghua University
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王 〓
Faculty Of Pharmaceutical Sciences Okayama University
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Wang Zhao
Department Of Biological Sciences And Biotechnology Tsinghua University
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Li X
Bioorganic Phosphorus Chemistry Laboratory Tsinghua University
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ZHOU Jiangbing
Department of Biological Science and Biotechnology, Tsinghua University
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JU Yong
Bioorganic Phosphorus Chemistry Laboratory, Tsinghua University
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ZHANG Hongjun
Department of Biological Science and Biotechnology, Tsinghua University
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LIU Mingjie
Department of Biological Science and Biotechnology, Tsinghua University
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LI Xue
Bioorganic Phosphorus Chemistry Laboratory, Tsinghua University
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Wang Z
Faculty Of Pharmaceutical Sciences Okayama University
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Li Xue
Bioorganic Phosphorus Chemistry Laboratory Tsinghua University
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Ju Yong
Key Laboratory Of Bioorganic Phosphorus Chemistry Department Of Chemistry Tsinghua University
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Zhang H
Department Of Biological Sciences And Biotechnology Tsinghua University
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Liu Mingjie
Department Of Biologcal Science And Biotechnology Tsinghua University
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Zhou Jiangbing
Department Of Biological Sciences And Biotechnology Tsinghua University
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Wang Zhao
Protein Sci. Key Lab. Of The Ministry Of Education School Of Medicine Tsinghua Univ.
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WANG Zhao
Department of Anesthesiology, Northwestern University Medical School
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