IMMUNOLOGICAL EFFECTS OF MOUSE CERULOPLASMIN
スポンサーリンク
概要
- 論文の詳細を見る
Mouse ceruloplasmin, the level of which in serum increases on administration of antitumor polysaccharides, was shown to have enhancing effects on the antibody production of mouse spleen cells toward sheep red blood cells and restorative effects on the suppressed mixed lymphocyte reaction of spleen cells of tumor-bearing mice. The proliferation of interleukin-2 dependent cytotoxic T cells and the suppressed concanavalin A response of the tumor bearing mice spleen cells were also enhanced by this serum glycoprotein, weakly but reproducibly. Furthermore, this serum glycoprotein was found to enhance glucose consumption and interleukin-1 production and cytotoxic activities of mouse peritoneal macrophages. These results suggest that mouse ceruloplasmin plays some roles in the natural resistance surveillance against tumors.
- 公益社団法人日本薬学会の論文
著者
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児島 英介
Division Of Chemical Toxicology And Immunochemistry Faculty Of Pharmaceutical Sciences University Of
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MITSUNO TOHRU
Division of Chemical Toxicology and Immunochemistry, Faculty of Pharmaceutical Sciences, University
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KOJIMA EISUKE
Division of Chemical Toxicology and Immunochemistry, Faculty of Pharmaceutical Sciences, University
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OSAWA TOSHIAKI
Division of Chemical Toxicology and Immunochemistry, Faculty of Pharmaceutical Sciences, University
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Osawa Toshiaki
Division Of Chemical Toxicology And Immunochemistry Faculty Of Pharmaceutical Sciences University Of
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Osawa Toshiaki
Laboratory Of Molecular Medicine Department Of Integrated Biosciences Graduate School Of Frontier Sc
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Kojima Eisuke
Division Of Chemical Toxicology Immunochemistry Faculty Of Pharmaceutical Sciences University Of Tok
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Mitsuno Tohru
Division Of Chemical Toxicology Immunochemistry Faculty Of Pharmaceutical Sciences University Of Tok
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OSAWA Toshiaki
Yakult Central Institute for Microbiological Research
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Osawa Toshiaki
Division Of Chemical Toxicology And Immunochemistry Faculty Of Pharmaceutical Science University Of
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