EFFECTS OF BUTYLATED HYDROXYTOLUENE (BHT) ON THE LEVEL OF GLUTATHIONE AND THE ACTIVITY OF GLUTATHIONE-S-TRANSFERASE IN RAT LIVER
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概要
- 論文の詳細を見る
Oral administration of 500 mg/kg of butylated hydroxytoluene (BHT) daily for three days elevated the total glutathione (GSH) level and the activities of GSH-S-transferase for CDNB and DCNB and GSSG reductase in the rat liver. BHT-alcohol, which is a metabolite of BHT, also elevated the level or activity of these components. The induction of these components with BHT-alcohol was slightly less than that with BHT. However, BHT or BHT-alcohol in doses used had no effect on GSH peroxidase activity.
- 公益社団法人日本薬学会の論文
著者
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Suga Tetsuya
Department Of Clinical Biochemistry Faculty Of Pharmaceutical Science Tokyo University Of Pharmacy A
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Suga Tetsuya
Department Of Clinical Biochemistry Tokyo College Of Pharmacy
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Hiraga Kogo
Department Of Toxicology Tokyo Metropolitan Research Labolatory Of Public Health
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Hiraga Kogo
Department Of Toxicology Tokyo Metropolitan Research Laboratory Of Public Health
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HIRAGA KOGO
Department of Pharmacology, the Tokyo Jikei-Kai School of Medicine
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