A Novel Cytotoxic C-Methylated Biflavone from the Stem of Cephalotaxus wilsoniana

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概要

• 論文の詳細を見る

• Bioassay-directed fractionation of an ethanolic extract of Cephalotaxus wilsoniana has resulted in the isolation of a novel C-methylated biflavone, taiwanhomoflavone-A (1). Its structure was elucidated on the basis of spectroscopic analysis. Taiwanhomoflavone-A is cytotoxic with ED_<50> values of 3.4,1.0,2.0 and 2.5 μg/ml, respectively, against KB epidermoid carcinoma of nasopharynx, COLO-205 colon carcinoma, Hepa-3B hepatoma, and Hela cervix tumor cells.

• 社団法人日本薬学会の論文
• 2000-03-01

著者

• Kuo Y‐h

  National Taiwan Univ. Taipei Twn

• LIN Chien-Huang

  Graduate Institute of Medical Sciences, Taipei Medical University

• Kuo Y‐h

  Ghent Univ. Gent Bel

• Li S‐y

  Chinese Culture Univ. Taipei Twn

• Kuo Yu-jen

  National Research Institute Of Chinese Medicine:school Of Pharmacy Taipei Medical University

• KUO Yao-Haur

  National Research Institute of Chinese Medicine

• LI Shyh-Yuan

  National Research Institute of Chinese Medicine

• Kuo Yao-haur

  National Res. Inst. Of Chinese Medicine Taiwan

• SHEN Ya-Ching

  School of Pharmacy, College of Medicine, National Taiwan University

• SHEN Ya-Ching

  Institute of Marine Resources, National Sun Yat-sen University

• LEE Yi-Ling

  National Research Institute of Chinese Medicine

• LIN Chin-Hou

  National Research Institute of Chinese Medicine

• HWANG Shy-Yuan

  Department of Agriculture and Forestry, Taiwan Endemic Species Research Institute

• Hwang Shy-yuan

  Division Of Botany. Taiwan Endemic Species Research Institute

• Kuo Yao-haur

  National Research Institute Of Chinese Medicine:school Of Pharmacy Taipei Medical University

• Kuo Yu-haey

  Department Of Biochemistry Faculty Of Medicine And Health Sciences Ghent University

• Kuo Yu-haey

  Laboratory Of Physiological Chemistry Faculty Of Medicine State University Of Ghent

• Lin C‐h

  National Cheng Kung Univ. Tainan Twn

• Shen Y‐c

  National Sun Yat‐sen Univ. Kaohsiung Twn

• Li Shyh-yuan

  National Research Institute Of Chinese Medicine:institute Of Applied Chemistry Chinese Culture Unive

• Lin Chien-huang

  Graduate Institute Of Medical Sciences Taipei Medical University

• Lee Yi-ling

  National Research Institute Of Chinese Medicine:department Of Chemistry Chinese Culture University

• Hwang Sue-yun

  Catholic Institute Of Immunobiology Catholic University Of Korea

• Shen Ya-ching

  Institute Of Marine Resources National Sun Yat-sen University

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