New Taxane Diterpenoids from the Roots of Taiwanese Taxus mairei

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概要

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• Five new taxane diterpenoids, taxumairols G(1), H(2), I(3), J(4), and L(5) were isolated from extracts of the roots of Taiwanese Taxus mairei (LEMEE & LEVL.) S. Y. Hu. Compounds 1-4 belong to the new 11(15→1)-abeo-taxene system, having a tetrahydrofuran ring along carbons C-2, C-3, C-4 and C-20. Compounds 3 and 4 contain an isopropenyl group at C-1 while compounds 1 and 2 are attached with a benzoxyl group at C-15. The structures of compounds 1-5 were determined on the basis of two-dimensional (2D)-NMR techniques including correlation spectroscopy (COSY), heteronuclear single quantum coherence (HSQC), heteronuclear multiple bond correlation (HMBC), and nuclear Overhauser effect spectroscopy (NOESY) experiments.

• 社団法人日本薬学会の論文
• 2002-06-01

著者

• Cheng Yuan-bin

  Department Of Marine Biotechnology And Resources National Sun Yat-sen University

• Kuo Y‐h

  National Taiwan Univ. Taipei Twn

• Lin Y‐c

  National Sun Yat‐sen Univ. Kaohsiung Twn

• Lin Yu-chi

  Institute Of Marine Resources National Sun Yat-sen University

• Kuo Y‐h

  Ghent Univ. Gent Bel

• Kuo Yu-jen

  National Research Institute Of Chinese Medicine:school Of Pharmacy Taipei Medical University

• KUO Yao-Haur

  National Research Institute of Chinese Medicine

• Lin Y‐c

  Institute Of Marine Resources National Sun Yat-sen University

• Kuo Yao-haur

  National Res. Inst. Of Chinese Medicine Taiwan

• SHEN Ya-Ching

  School of Pharmacy, College of Medicine, National Taiwan University

• SHEN Ya-Ching

  Institute of Marine Resources, National Sun Yat-sen University

• CHANG Yao-To

  Institute of Marine Resources, National Sun Yat-sen University

• LIN Chung-Ling

  Institute of Marine Resources, National Sun Yat-sen University

• CHEN Ching-Yeu

  Institute of Marine Resources, National Sun Yat-sen University

• Kuo Yao-haur

  National Research Institute Of Chinese Medicine:school Of Pharmacy Taipei Medical University

• Kuo Yu-haey

  Department Of Biochemistry Faculty Of Medicine And Health Sciences Ghent University

• Kuo Yu-haey

  Laboratory Of Physiological Chemistry Faculty Of Medicine State University Of Ghent

• Shen Y‐c

  National Sun Yat‐sen Univ. Kaohsiung Twn

• Liaw Chia-ching

  Department Of Marine Biotechnology And Resources National Sun Yat-sen University

• Chen C‐y

  National Sun Yat‐sen Univ. Kaohsiung Twn

• Shen Ya-ching

  Institute Of Marine Resources National Sun Yat-sen University

• Chen Ching-yeu

  Institute Of Marine Resources National Sun Yat-sen University

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