Convenient Synthesis of 5-Trifluoroacetylated Imidazoles by Ring Transformation of Mesoionic 1,3-Oxazolium-5-olates
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概要
- 論文の詳細を見る
Mesoionic 4-trifluoroacetyl-1,3-oxazolium-5-olates (1), obtained from the reaction of N-acyl-N-alkylglycines (2) with trifluoroacetic anhydride, react with amidines to give 5-trifluoroacetylimidazoles (3) in moderate yield. The novel ring trandformations of 1 into 3 occur via an initial attack of amidines on the C-2 position of the ring.
- 公益社団法人日本薬学会の論文
- 2000-03-01
著者
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Saito Setsuo
Faculty of Pharmaceutical Science,Josai University
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Kawase Masami
Faculty Of Pharmaceutical Sciences Josai University
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Saito Setsuo
Faculty Of Pharmaceutical Sciences Josai University
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