Autoxidation of Intermediary Mesoionic 1,3-Oxazolium-5-olates Generated from Cyclic N-Acyl α-Amino Acids
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概要
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Mesoionic 1,3-oxazolium-5-olates (munchnones) react fairly rapidly with oxygen to give the autoxidation products when the C-4 substituent is aromatic. The autoxidation occurred in the munchnones generated from N-acyl tetrahydroisoquinoline-1-carboxylic acids or tetrahydro-β-carboline-1-carboxylic acids. The mechanism was elucidated by ^<18>O labeling experiments and involved a series of well-precedented autoxidative processes including oxygenation, cyclization of the resulting peroxy anion, and oxidative cleavage.
- 公益社団法人日本薬学会の論文
- 1997-08-15
著者
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KAWASE Masami
Faculty of Pharmaceutical Sciences, Josai University
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Kawase Masami
Faculty Of Pharmaceutical Sciences Josai University
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