A General Method for the Preparation of 5-Trifluoromethylated Oxazoles from α-Amino Acids
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概要
- 論文の詳細を見る
The reactions of N-acyl-N-benzyl-α-amino acids (1) or N-acylprolines (5) with trifluoroacetic anhydride in the presence of pyridine afford 5-trifluoromethyloxazoles (2 or 7) in good yields. The reaction could proceed through the transient formation of mesoionic 1,3-oxazolium-5-olates, followed by oxazolium salts.
- 公益社団法人日本薬学会の論文
- 1998-05-15
著者
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Kurihara T
Josai Univ. Saitama Jpn
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Kurihara Teruo
Faculty Of Science Josai University
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KAWASE Masami
Faculty of Pharmaceutical Sciences, Josai University
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Miyamae H
Josai Univ. Saitama Jpn
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Miyamae Hiroshi
Faculty Of Science Josai University
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Kawase Masami
Faculty Of Pharmaceutical Sciences Josai University
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