Synthesis of Isoquinoline Derivatives by Diels-Alder Reactions of 2(1H)-Pyridones Having an Electron-withdrawing Group with Methoxy-1,3-butadienes
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概要
- 論文の詳細を見る
Diels-Alder (DA) reactions of 2(1H)-pyrodines having an electron-withdrawing group at the 4-position with 2,3-dimethoxy- and 2-methoxy-1,3-butadienes gave isoquinoline derivatives. Furthermore, an isoquinoline alkaloid (6,7-dimethoxy-2-methyl-1(2H)-isoquinolone) was synthesized by elimination of hydrogen cyanide and dehydrogenation of the DA-adduct having a cyano group at the 4a-position.
- 公益社団法人日本薬学会の論文
- 2000-11-01
著者
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FUJITA Reiko
Tohoku Pharmaceutical University
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TOMISAWA Hiroshi
Tohoku Pharmaceutical University
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Fujita R
Tohoku Pharmaceutical University
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Fujita R
Department Of Chemistry School Of Liberal Arts And Sciences Iwate Medical University
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Hoshino M
Tohoku Pharmaceutical University
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HOSHINO Masato
Tohoku Pharmaceutical University
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HONGO Hiroshi
Tohoku Pharmaceutical University
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Hongo H
Tohoku Pharmaceutical University
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Tomisawa H
Tohoku Pharmaceutical University
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- Cycloaddition of 2(1H)-Pyridones Having a Methoxycarbonyl Group to 1, 3-Butadiene Derivatives
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