Reaction of 1-Alkylthioisoquinolinium Salts with Active Methylene Compounds
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概要
- 論文の詳細を見る
2-Alkyl-1-alkylthioisoquinolinium salts were readily prepared from 2-alkyl-1(2H)-isoquinolones via 2-alkyl-1(2H)-thioisoquinolones in two steps. Under mild conditions, the reaction of 2-alkyl-1-alkylthioisoquinolinium salts with active methylene compounds in the presence of sodium hydride afforded 2-alkyl-1-(substituted methylene)iso-quinolines in good yields. Pyrrolo[2, 1-a]isoquinolines were synthesized by the cyclization of 2-benzyl-1-(substituted methylene)isoquinolines using acetic anhydride.
- 公益社団法人日本薬学会の論文
- 2002-02-01
著者
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Watanabe Noriyuki
Tohoku Pharmaceutical University
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FUJITA Reiko
Tohoku Pharmaceutical University
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TOMISAWA Hiroshi
Tohoku Pharmaceutical University
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Fujita R
Tohoku Pharmaceutical University
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Fujita R
Department Of Chemistry School Of Liberal Arts And Sciences Iwate Medical University
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Tomisawa H
Tohoku Pharmaceutical University
関連論文
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- Diels-Alder Reaction of 2(1H)-Pyridones Acting as Dienes
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